Clinical Trials in Pittsburgh

Showing 3241-3260 of 21,047 trials

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

NCT04354077

This is a pilot study to evaluate the safety and efficacy of deep brain stimulation (DBS) of the nucleus accumbens (NAc) as adjunctive treatment for treatment-refractory opioid use disorder. This study will include 3 individuals with opioid use disorder and relapsing opioid use despite active participation in a drug addiction treatment program.

Opioid-use Disorder

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)3 participantsStarted Feb 2022

Pittsburgh, Pennsylvania, United States

RECRUITINGNA< 1 mile

Effect of Raised End-Tidal pCo2 on Choroidal Volume

NCT06275308

This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated intraoperative OCT imaging under eye exams under anesthesia.

Intraocular Pressure

University of Pittsburgh20 participantsStarted Feb 2023

Pittsburgh, Pennsylvania, United States

Active Not RecruitingNA< 1 mile

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study

NCT03901807

Prospective, multicenter, randomized, open-label study of standard of care plus the PMX cartridge versus standard of care alone in patients with endotoxemic septic shock

Septic ShockEndotoxemia

Spectral Diagnostics (US) Inc.150 participantsStarted Jan 2020

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • San Francisco, California, United States +17 more locations

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

Effect of Raised End-Tidal pCo2 on Choroidal Volume

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study

Find Trials by Condition in Pittsburgh

A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

STimulation to Activate RespIration

ASSESS ALL ALS Study

The PROTEMBO Trial

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome

Supporting Parents in Affirming Their Children's Experiences of Stigma

Study of Immunotherapy (Sasanlimab) in Combination With Targeted Therapies in People With Advanced Non-small Cell Lung Cancer (NSCLC) (Landscape 1011 Study)

IC-8 Apthera IOL New Enrollment Post Approval Study

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Discharge Stewardship in Children's Hospitals

Randomized Withdrawal Study in Patients With Schizophrenia

Pragmatic Use of PAIN-Advanced Dementia Scale in Emergency Departments

CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes