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Clareo Health | Clinical Trials in Pittsburgh | 10,682 Studies Near You

Clinical TrialsPittsburgh

Clinical Trials in Pittsburgh

Discover 10,682 clinical trials near Pittsburgh, Pennsylvania. Find research studies in your area.

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma Pancreatic Cancer

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 261-280 of 10,682 trials

CompletedTrial of Sacituzumab Govitecan in Participants With Refractory/Relapsed Metastatic Triple-Negative Breast Cancer (TNBC)The primary objective of this study is to compare the efficacy of sacituzumab govitecan to the treatment of physician's choice (TPC) as measured by independently-reviewed…NCT02574455·Daphne, Alabama and 229 others

Find Trials by Condition in Pittsburgh

Breast Cancerin Pittsburgh Lung Cancerin Pittsburgh Prostate Cancerin Pittsburgh Colorectal Cancerin Pittsburgh Melanomain Pittsburgh Leukemiain Pittsburgh Lymphomain Pittsburgh Pancreatic Cancerin Pittsburgh Ovarian Cancerin Pittsburgh Brain Cancerin Pittsburgh

Data from ClinicalTrials.govTerms

CompletedSafety and Efficacy Following Repeat-Dose of Evinacumab (Anti-ANGPTL3) in Patients With Severe Hypertriglyceridemia (sHTG) at Risk for Acute PancreatitisThe primary objective is to determine the change in Triglyceride (TG) levels following 12 weeks of repeated Intravenous (IV) doses of evinacumab.NCT03452228·Boca Raton, Florida and 16 others

RecruitingEfficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab…NCT05281471·Mobile, Alabama and 32 others

WithdrawnPharmacokinetics and Pharmacodynamics of MTR105 in Hypotensive Cardiac Surgery PatientsThe purpose of this study is to evaluate the safety, pharmacokinetic and the pharmacodynamic effects of escalating doses of MTR105 while weaning from bypass in a hypotensive…NCT00482287·Pittsburgh, Pennsylvania

CompletedA Study of Melphalan Flufenamide (Melflufen) Plus Dexamethasone in Patients With Relapsed or Refractory Multiple MyelomaThis study will evaluate melflufen in combination with dexamethasone in adult patients with relapsed or refractory multiple myeloma in whose disease is refractory to pomalidomide…NCT02963493·Whittier, California and 19 others

TerminatedNY-ESO-1 Vaccine in Combination With Ipilimumab in Patients With Unresectable or Metastatic MelanomaThis was a Phase 1, open-label, non-randomized study of the combination of NY-ESO-1 plus ipilimumab in patients with unresectable or metastatic melanoma for whom treatment with…NCT01810016·New York, New York and 4 others

CompletedStudy of Fluticasone Propionate Multidose Dry Powder Inhaler Compared With Fluticasone Propionate/Salmeterol Multidose Dry Powder InhalerThis study is to evaluate the safety and efficacy of fluticasone propionate and fluticasone propionate salmeterol in pediatric participants with a documented history of persistent…NCT02980133·Birmingham, Alabama and 117 others

CompletedStudy of Bendamustine Hydrochloride and Rituximab (BR) Compared With R-CVP or R-CHOP in the First-Line Treatment of Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL) - Referred to as the BRIGHT StudyThe primary objective of the study is to compare the complete response (CR) rate of bendamustine and rituximab (BR) with that of standard treatment regimens of either rituximab…NCT00877006·Tucson, Arizona and 127 others

CompletedGene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR GeneA clinical trial of AAV5-RPGR vector for participants with X-linked retinitis pigmentosa (XLRP)NCT04671433·La Jolla, California and 27 others

CompletedThe Development and Evaluation of a Novel Duodenoscope Assessment ToolEndoscopic retrograde cholangiopancreatography (ERCP) procedures are performed using duodenoscopes for the treatment of pancreatic and biliary diseases.NCT04004533·Little Rock, Arkansas and 8 others

RecruitingRESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory MyopathyRESET-Myositis: Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects with Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory…NCT06154252·Orange, California and 34 others

CompletedEffects of Metformin in a Non-Diabetic Patient PopulationMetformin has a well-established safety profile and it has become clear that metformin has additional salutary effects, including anti-inflammatory, anti-aging, and…NCT03772964·Pittsburgh, Pennsylvania

CompletedA Gene Transfer Study for Hemophilia AThis clinical research study is being conducted by Spark Therapeutics, Inc. to determine the safety and efficacy of the factor VIII gene transfer treatment with SPK-8011 in…NCT03003533·Sacramento, California and 15 others

CompletedEvaluation of the GORE Conformable TAG® for Treatment of Traumatic TransectionTAG 08-02 is a prospective, multicenter, single-arm study to evaluate the use of the CTAG Device in traumatic transection of the descending thoracic aorta.NCT00917852·Los Angeles, California and 25 others

TerminatedPROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on ApixabanCurrently, warfarin is the only approved anticoagulation for patients with mechanical valves.NCT04142658·Tucson, Arizona and 61 others

WithdrawnNomacopan Therapy in Adult Patients With Bullous Pemphigoid Receiving Adjunct Oral Corticosteroid Therapy (ARREST-BP)A phase III two-part study of nomacopan, a bifunctional inhibitor of complement component C5 and leukotriene B4 (LTB4), for the treatment of moderate and severe bullous pemphigoid.NCT05061771·Los Angeles, California and 11 others

CompletedGlucose to Goal: A Model to Support Diabetes Management in Primary CareDiabetes education is a very important part of diabetes care. Most people with diabetes receive care in primary care practices where diabetes education is not always available.NCT02715934·Pittsburgh, Pennsylvania

RecruitingNear-InfraRed Spectroscopy of Auricular StimulationThis is a single-visit non-invasive study of healthy volunteer subjects.NCT06825364·Pittsburgh, Pennsylvania

CompletedTargeted Multidomain (T-MD) Interventions for Complex Mild Traumatic Brain Injury (mTBI)Objective: This 3-year multisite RCT will determine the effectiveness of a targeted multidomain intervention (T-MD) (anxiety/mood, cognitive, migraine, ocular, vestibular; and…NCT04549532·Pittsburgh, Pennsylvania and 1 other

CompletedSafety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFEThis was a multicenter, randomized (1:1 inhaled treprostinil: placebo), double-blinded, placebo-controlled trial to evaluate the safety and efficacy of inhaled treprostinil in…NCT02630316·Birmingham, Alabama and 96 others

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