Clinical Trials in Pittsburgh

Showing 2021-2040 of 10,050 trials

Lithium As a Treatment to Prevent Impairment of Cognition in Elders

NCT03185208

Alzheimer's disease (AD) is the most common cause of dementia in adults 65 years and older. AD leads to a complete loss of memory and independent function, and presently there is no cure. Many studies suggest that lithium treatment may delay dementia onset or slow its progression. However, more research is needed to understand the extent of its anti-dementia properties if it will be deployed broadly in the general population. This study will examine whether lithium has anti-dementia properties in older adults who have mild cognitive impairment and are at risk of becoming demented.

Mild Cognitive Impairment

Ariel Gildengers, MD83 participantsStarted Feb 2018

Pittsburgh, Pennsylvania, United States

RECRUITINGNA< 1 mile

Biennial CEM in Women With a Personal History of Breast Cancer

NCT06105749

This is a prospective clinical trial that will examine if biennial contrast-enhanced mammography added to annual 3D mammography (tomosynthesis) substantially improves breast cancer detection with minimal increase in false-positives, in women with a personal history of breast cancer.

Breast CancerBreast NeoplasmsBreast Cancer Female+1 more

Wendie Berg1,500 participantsStarted Nov 2023

Bethel Park, Pennsylvania, United States • Cranberry Township, Pennsylvania, United States • Monroeville, Pennsylvania, United States +3 more locations

Lithium As a Treatment to Prevent Impairment of Cognition in Elders

Biennial CEM in Women With a Personal History of Breast Cancer

Find Trials by Condition in Pittsburgh

Development and Testing of imHere4U: A Digital Suicide Prevention Intervention for Cyberbullied Adolescents

A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04)

Abatacept in Immune Checkpoint Inhibitor Myocarditis

Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell Carcinoma

A Study of mRNA-1010 Compared With a Licensed Influenza Vaccine in Adults ≥50 Years of Age

A Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community Setting

Phase 2a Study of the Safety, Tolerability, and Pharmacokinetics of Topically Administered PRN473 (SAR444727) in Patients With Mild to Moderate Atopic Dermatitis

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy

A Phase 2a Study Evaluating BIVV020 in Adults With Persistent/Chronic Immune Thrombocytopenia (ITP)

Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI)

Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants

Study of mRNA Vaccine Formulation Against COVID-19 in Healthy Adults 18 Years of Age and Older

A Study of an Investigational Flu Seasonal/SARS-CoV-2 Combination Vaccine in Adults

LiveSMART Trial to Prevent Falls in Patients With Cirrhosis

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy