Clinical Trials in Pittsburgh

Showing 2001-2020 of 10,050 trials

Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With Phenylketonuria

NCT05270837

This is a Phase 3 open-label randomized controlled study enrolling approximately 54 adolescents with PKU. The study is designed to assess the safety and efficacy of pegvaliase injections.

Phenylketonuria (PKU)

BioMarin Pharmaceutical55 participantsStarted Jun 2022

Phoenix, Arizona, United States • Little Rock, Arkansas, United States • Aurora, Colorado, United States +13 more locations

COMPLETEDNA< 1 mile

Multi-hospital Electronic Decision Support for Drug-associated Acute Kidney Injury

NCT06264752

This study is a randomized controlled trial at eight hospitals within the University of Pittsburgh Medical Center-UPMC system. The project will assess the efficacy of a clinical surveillance system augmented with near real-time predictive analytics to support a pharmacist-led intervention delivered to attending physicians (primary service) to reduce the progression and complications of drug-associated acute kidney injury (D-AKI) in hospitalized (non-ICU) adults.

Acute Kidney Injury

University of Pittsburgh698 participantsStarted Feb 2024

Altoona, Pennsylvania, United States • Farrell, Pennsylvania, United States • McKeesport, Pennsylvania, United States +5 more locations

Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With Phenylketonuria

Multi-hospital Electronic Decision Support for Drug-associated Acute Kidney Injury

Find Trials by Condition in Pittsburgh

Molecular Basis of Pediatric Liver Cancer

Cross-Seal Closure Device IDE Trial - Study of the Cross-SealTM Suture-Mediated Vascular Closure Device System

The Use of Mentoring to Promote Well-being for Female SMART Members

Tailored vs. Anatomical Ablation Strategy for Persistent Atrial Fibrillation

Clinical Utility of Residual Hearing in the Cochlear Implant Ear

A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)

A Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

BlueWind RENOVA iStim™ System for the Treatment of OAB

The Pediatric Artificial Pancreas Automated Initialization Trial

Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older

Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children

A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression

PRO 140 in Treatment-Experienced HIV-1 Subjects

Periprosthetic Fracture Registry (PPFx)

First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

A Dose-Range Study of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity

A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Parkinson's Disease Mild Cognitive Impairment (PD-MCI)