Clinical Trials in Philadelphia

Showing 7241-7260 of 20,904 trials

Natural History Study of ENPP1 Deficiency and the Early-onset Form of ABCC6 Deficiency

NCT05050669

The purpose of this prospective study is to characterize the natural history of ENPP1 Deficiency and the early-onset form of ABCC6 Deficiency longitudinally. The study will prospectively gather information about the biochemical, physiological, anatomic, radiographic, and functional manifestations (including patient reported outcomes) of each disease.

Ectonucleotide Pyrophosphatase/phosphodiesterase1 DeficiencyATP-Binding Cassette Subfamily C Member 6 DeficiencyGeneralized Arterial Calcification of Infancy+1 more

Inozyme Pharma12 participantsStarted Apr 2022

Boston, Massachusetts, United States • Philadelphia, Pennsylvania, United States • Fort Worth, Texas, United States +2 more locations

COMPLETEDPhase 2< 1 mile

Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis

NCT03112681

prospective, multicenter, randomized, double-blind, placebo-controlled study to evaluate safety, tolerability and efficacy of saroglitazar magnesium 2 mg, 4 mg in Patients with Primary Biliary Cholangitis (PBC). A total 36 subjects will be enrolled in a ratio of 1:1:1 to receive either saroglitazar magnesium 2 mg or saroglitazar magnesium 4 mg or placebo.

Primary Biliary Cirrhosis

Zydus Therapeutics Inc.37 participantsStarted Aug 2017

Pasadena, California, United States • Miami, Florida, United States • Marietta, Georgia, United States +6 more locations

Natural History Study of ENPP1 Deficiency and the Early-onset Form of ABCC6 Deficiency

Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis

Find Trials by Condition in Philadelphia

Pembrolizumab and Reirradiation in Bevacizumab Naïve and Bevacizumab Resistant Recurrent Glioblastoma

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Pilot Trial of the RUBI Program for Autistic Adults

Investigating the Effect of Obicetrapib on Lipoprotein Metabolism

Mendelian Reverse Cholesterol Transport Study

A First-in-Human Study to Evaluate JCXH-105, an SrRNA-based Herpes Zoster Vaccine

Study of Daxdilimab (HZN-7734) for the Treatment of Systemic Lupus Erythematosus in an Open-label Extension Study

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

Peer Mentorship to Improve Outcomes in Patients on Maintenance Hemodialysis

International Weight Control Registry

Umbilical Cord Milking in Non-Vigorous Infants

TelemEdiciNe-bAsed Cognitive TherapY for Migraines

Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

Air Optix® Night and Day® Aqua Continuous Wear

Study of AZD9291 Plus MEDI4736 Versus AZD9291 Monotherapy in NSCLC After Previous EGFR TKI Therapy in T790M Mutation Positive Tumours

A Study to Evaluate the Efficacy, Safety, and Concentration of SNS812 in Mild to Moderate COVID-19 Patients

Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry