Clinical Trials in Philadelphia

Showing 7261-7280 of 20,904 trials

Natural History Study of ENPP1 Deficiency and the Early-onset Form of ABCC6 Deficiency

NCT05050669

The purpose of this prospective study is to characterize the natural history of ENPP1 Deficiency and the early-onset form of ABCC6 Deficiency longitudinally. The study will prospectively gather information about the biochemical, physiological, anatomic, radiographic, and functional manifestations (including patient reported outcomes) of each disease.

Ectonucleotide Pyrophosphatase/phosphodiesterase1 DeficiencyATP-Binding Cassette Subfamily C Member 6 DeficiencyGeneralized Arterial Calcification of Infancy+1 more

Inozyme Pharma12 participantsStarted Apr 2022

Boston, Massachusetts, United States • Philadelphia, Pennsylvania, United States • Fort Worth, Texas, United States +2 more locations

COMPLETEDPhase 3< 1 mile

A Safety and Efficacy Study in Patients With Gastric Cancer

NCT00400179

This is an open-label, international, two-arm, parallel, randomized, Phase 3 study evaluating the efficacy and safety of S-1/cisplatin versus 5-FU/cisplatin in patients with advanced gastric cancer previously untreated with chemotherapy for advanced disease. Patients will be randomly assigned (1:1) to S-1/cisplatin (experimental arm) or 5-FU/cisplatin (control arm). Patients will be stratified by number of metastatic sites (one vs. more than one), locally advanced or metastatic disease, prior adjuvant therapy (yes or no), measurable or non-measurable disease, and center.

Gastric Cancer

Taiho Oncology, Inc.1,053 participantsStarted May 2005

Huntsville, Alabama, United States • Burbank, California, United States • Gilroy, California, United States +30 more locations

Natural History Study of ENPP1 Deficiency and the Early-onset Form of ABCC6 Deficiency

A Safety and Efficacy Study in Patients With Gastric Cancer

Find Trials by Condition in Philadelphia

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)

Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006)

Clinical Evaluation of the i-STAT TBI Test

Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control As a Means of Improving Glycemic Control in Adults with Type 2 Diabetes Mellitus

ADVANCE- Automated Detection and Volumetric Assessment of ICH

A Study to Determine Dose and Regimen of Durvalumab as Monotherapy or in Combination With Pomalidomide With or Without Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma

Strategies to Assist With Management of Pain

Peer Mentorship to Improve Outcomes in Patients on Maintenance Hemodialysis

International Weight Control Registry

An Open-Label Extension Study for Patients With Duchenne Muscular Dystrophy Who Participated in Studies of SRP-5051 (Vesleteplirsen)

Pharmacokinetics and Pharmacodynamics of Rifaximin Novel Formulations in Patients With Sickle Cell Disease

A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

A Randomized Phase 2 Trial of TAS-114 in Combination With S-1 Versus S-1

Music Therapy Songwriting and Mental Health in Neonatel Intensive Care Unit (NICU) Parents

Acupuncture for Preterm Infants Requiring Eye-exam