Clinical Trials in Philadelphia

Showing 7261-7280 of 15,860 trials

Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia

NCT01362595

This study will determine the safety and possibility of giving the amino acid, leucine, in patients with Diamond Blackfan anemia(DBA)who are on dependent on red blood cell transfusions. The leucine is expected to produce a response in patients with DBA to the point where red blood cell production is increased. Red cell transfusions can then be less frequent or possibly discontinued. The investigators will study the side effects, if any, of giving leucine to DBA patients. Leucine levels of leucine will be obtained at baseline and during the study. The drug leucine will be provided in capsule form and taken 3 times a day for a total of 9 months.

Diamond Blackfan AnemiaBlackfan Diamond SyndromeDBA+2 more

Northwell Health55 participantsStarted Jun 2013

Phoenix, Arizona, United States • Palo Alto, California, United States • Indianapolis, Indiana, United States +8 more locations

TERMINATEDPhase 3< 1 mile

Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

NCT00858364

This is a study in patients with chemotherapy induced anemia receiving multi-cycle chemotherapy for the treatment of stage IV non-small cell lung cancer (NSCLC). The primary objective of the study is to demonstrate that overall survival (OS) is not worse in participants on darbepoetin alfa treated to a hemoglobin ceiling of 12.0 g/dL compared to participants treated with placebo.

Non-Small Cell Lung CancerAnemiaCancer+1 more

Amgen2,549 participantsStarted Jul 2009

Anniston, Alabama, United States • Birmingham, Alabama, United States • Anchorage, Alaska, United States +563 more locations

Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia

Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

Find Trials by Condition in Philadelphia

Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)

Study to Assess Darbepoetin Alfa Dosing for the Correction of Anemia in Pediatric Patients With Chronic Kidney Disease

Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid Malignancies

Persistence With Prolia® (Denosumab) in Postmenopausal Women With Osteoporosis

A Study of Use of Ella®, an Emergency Contraceptive, Under Simulated OTC Conditions

A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE-BRAVE II)

Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian Cancer

DEBUT: Diverticulitis Evaluation of Patient Burden, Utilization, and Trajectory

Low-Level Laser Therapy Treatment of Lung Inflammation in Post-COVID-19 Recovery

The International Diabetes Closed Loop (iDCL) Trial: Protocol 1

Addition of ISIS 14803 to Therapy With Peginterferon and Ribavirin for Chronic Hepatitis C (HCV) Patients Not Responding Adequately to the Two Drugs

The International Diabetes Closed Loop (iDCL) Trial: Protocol 4

Project 1, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Childbearing Age Women

Project 2, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Opioid Abusers

Study to Evaluate the Efficacy/Safety of IPI-549 in Combination With Nivolumab in Patients With Advanced Urothelial Carcinoma (MARIO-275)

Safety Study of Nivolumab to Treat Advanced or Metastatic Non-small Cell Lung Cancer

A Prospective, Epidemiological Study to Assess the Disease Burden of Respiratory Syncytial Virus Associated, Suspected Lower Respiratory Tract Infections in Newborns, From 0 to 2 Years of Age and Risk of Development of Wheeze and Asthma From 0 to 6 Years of Age

A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes.