Clinical Trials in Philadelphia

Showing 7221-7240 of 20,904 trials

Checklist for AI in Medical Imaging (CLAIM) Consensus Panel

NCT05984082

The investigators will revise the Checklist for AI in Medical Imaging (CLAIM) guideline using Delphi consensus methods. An international panel of physicians, researchers, and journal editors with expertise in AI in medical imaging -- including radiology, pathology, dermatology, GI endoscopy, and ophthalmology -- will complete up to 3 web-based surveys. Participants who complete all survey rounds will be credited as contributors on resulting publications.

Artificial IntelligenceMachine LearningDiagnostic Imaging

University of Pennsylvania72 participantsStarted Aug 2023

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease

NCT04376684

OSCAR (Otilimab in Severe COVID-19 Related Disease) is a multi-center, double-blind, randomized, placebo-controlled trial to assess the efficacy and safety of otilimab for the treatment of severe pulmonary COVID-19 related disease. The study is being conducted in 2 parts (Part 1 and Part 2). Otilimab is a human monoclonal anti-granulocyte macrophage colony stimulating factor (GM-CSF) antibody that has not previously been tested in participants with severe pulmonary COVID-19 related disease in Part 1. The aim of this study is to evaluate the benefit-risk of a single infusion of otilimab in the treatment of hospitalized participants with severe COVID-19 related pulmonary disease with new onset hypoxia requiring significant oxygen support or requiring early invasive mechanical ventilation (less than or equal to \[\<=\] 48 hours before dosing). Participants will be randomized to receive a single intravenous (IV) infusion of otilimab or placebo, in addition to standard of care.

Severe Acute Respiratory Syndrome

GlaxoSmithKline1,156 participantsStarted May 2020

Mobile, Alabama, United States • Little Rock, Arkansas, United States • Sacramento, California, United States +117 more locations

Checklist for AI in Medical Imaging (CLAIM) Consensus Panel

Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease

Find Trials by Condition in Philadelphia

Mendelian Reverse Cholesterol Transport Study

Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis

A Study of Semorinemab in Patients With Moderate Alzheimer's Disease

Palbociclib in Real World Practice

A Study of Rilematovir (JNJ-53718678) in Adult Outpatients With Respiratory Syncytial Virus (RSV) Infection

A Study on the Immune Response and Safety Elicited by a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Influenza in Adults Aged 65 Years and Above

Study of Daxdilimab (HZN-7734) for the Treatment of Systemic Lupus Erythematosus in an Open-label Extension Study

Extension Study of Patidegib Topical Gel, 2% in Subjects With Gorlin Syndrome (Basal Cell Nevus Syndrome)

Prostate Imaging Using MRI +/- Contrast Enhancement

A Study to Characterize the Outcomes of Olaparib Maintenance Monotherapy in Newly Diagnosed BRCAwt Ovarian Cancer

Open-label Extension Study in Patients 65 Years or Older With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

TelemEdiciNe-bAsed Cognitive TherapY for Migraines

A Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's Disease or Ulcerative Colitis

An Open-Label Study of Trofinetide for the Treatment of Girls Two to Five Years of Age Who Have Rett Syndrome

Immunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin Cancers

Study of a Combination of GSK1795091 and Immunotherapies in Subjects With Advanced Solid Tumors

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations

Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry