Clinical Trials in Philadelphia

Showing 4701-4720 of 20,904 trials

PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

NCT03763643

This is a pilot/feasibility, multicenter, randomized, open label, clinical trial to test that hypothesis that plasmapheresis plus rituximab prior to or at the time of kidney transplantation can prevent recurrent FSGS in children and adults.

Focal Segmental Glomerulosclerosis

University of Minnesota21 participantsStarted Jul 2019

Tuscaloosa, Alabama, United States • Davis, California, United States • Chicago, Illinois, United States +9 more locations

RECRUITINGPhase 3< 1 mile

Abatacept in Immune Checkpoint Inhibitor Myocarditis

NCT05335928

The primary aim is to test whether abatacept, as compared to placebo, is associated with a reduction in major adverse cardiac events (MACE) among participants hospitalized with myocarditis secondary to an immune checkpoint inhibitor (ICI). The primary outcome, MACE, is a composite of first occurrence of cardiovascular death, non-fatal sudden cardiac arrest, cardiogenic shock, significant ventricular arrythmias, significant bradyarrythmias, or incident heart failure.

Myocarditis AcuteCancer

Massachusetts General Hospital390 participantsStarted Jul 2022

Los Angeles, California, United States • Los Angeles, California, United States • Washington D.C., District of Columbia, United States +28 more locations

PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

Abatacept in Immune Checkpoint Inhibitor Myocarditis

Find Trials by Condition in Philadelphia

Physiologic MR Imaging of Salivary Gland Tumors

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

A Trial of Centanafadine Efficacy, Safety, and Tolerability in Adult Subjects With Binge Eating Disorder

A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

A Phase I/II Study of Hypofractionated Proton Therapy for Stage II-III Non-Small Cell Lung Cancer

Regorafenib in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma

A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)

Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell Carcinoma

A Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community Setting

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus

OCS DCD Heart + CAP Continued Follow-Up

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

PLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning

A Study to Assess the Safety and Tolerability of BMS-986158 Alone and in Combination With Either Ruxolitinib or Fedratinib in Participants With Blood Cancer (Myelofibrosis)

A Phase 2a Study Evaluating BIVV020 in Adults With Persistent/Chronic Immune Thrombocytopenia (ITP)

Study of an Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers

A First-in-Human Dose Escalation and Expansion Study to Evaluate Intratumoral Administration of SAR441000 as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Phase 2a Study of the Safety, Tolerability, and Pharmacokinetics of Topically Administered PRN473 (SAR444727) in Patients With Mild to Moderate Atopic Dermatitis