EndoRotor DEN (Direct Endoscopic Necrosectomy)Trial

Exclusion Criteria

• •1. Subject unable to give informed consent.
• •2. Subject is unwilling to return for repeated endoscopies.
• •3. Documented Pseudoaneurysm \> 1cm within the WOPN
• •4. Intervening gastric varices or unavoidable blood vessels within the access tract (visible using endoscopy or endoscopic ultrasound).
• •5. Dual antiplatelet therapy or therapeutic anticoagulation that cannot be withheld for the procedure
• •6. Any condition that in the opinion of the investigator would create an unsafe clinical situation that would not allow the patient to safely undergo an endoscopic procedure (lack of medical clearance).
• •7. Pregnant or lactating women or women of childbearing potential who do not employ a reliable method of contraception as judged by the Investigator, and/or are not willing to use reliable contraception for the duration of study participation.
• •8. Patient is known to be currently enrolled in another investigational trial that could interfere with the endpoint analyses of this trial.