Clinical Trials in Philadelphia

Showing 4341-4360 of 15,860 trials

Contrast-enhanced Ultrasound Evaluation of Chemoembolization

NCT02764801

The primary objective of this trial is to evaluate the sensitivity and specificity of 2D and 4D contrast enhanced ultrasound for monitoring transarterial chemoembolization (TACE) response 1-2 weeks and 1 month post treatment as an alternative to contrast-enhanced magnetic resonance (MRI) or computed tomography (CT) imaging

Hepatocellular CarcinomaChemoembolization, Therapeutic

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University131 participantsStarted Apr 2016

La Jolla, California, United States • Philadelphia, Pennsylvania, United States • Philadelphia, Pennsylvania, United States

COMPLETED< 1 mile

Retrospective Clinical Trial Comparing Radiologists' Diagnosis Accuracy in Lung Cancer Screening Population With and Without the Help of an AI/ML Tech-based SaMD

NCT06751576

This is a two arm, randomized, controlled, blinded, multi-case multi reader (MRMC), retrospective study for the evaluation of the efficacy and safety of an AI/ML technology-based CADe/x developed to detect, localize and characterize malignancy score of pulmonary nodules on LDCT chest scans taken as part of a lung cancer screening program. LDCT DICOM images of patients who underwent routine lung cancer screening will be selected and enrolled into the study. Enrolled scans analyzed by radiologists with the assistance of the Median LCS (formerly iBiopsy) device are compared to the analysis by radiologists without the assistance of the Median LCS device. Figures of merit for patient level and lesion level detection and diagnostic efficacy will be calculated and compared, sub-class analysis will be performed to ensure device generalizability.

High Risk CancerLung Cancer

Median Technologies480 participantsStarted Sep 2022

Philadelphia, Pennsylvania, United States • Memphis, Tennessee, United States • Houston, Texas, United States +2 more locations

Contrast-enhanced Ultrasound Evaluation of Chemoembolization

Retrospective Clinical Trial Comparing Radiologists' Diagnosis Accuracy in Lung Cancer Screening Population With and Without the Help of an AI/ML Tech-based SaMD

Find Trials by Condition in Philadelphia

Preventing Distracted Driving Phase II

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease

Nausea and Vomiting In Patients Receiving Consecutive Days of Cisplatin

ZD1839 With Hypofractionated Radiation Therapy With an Immobilization Device for Advanced Non-Small Cell Lung Cancer

Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:

Study on the Safety and Effectiveness of VELCADE® in the Treatment of Graft-Versus-Host Disease

Increasing Colorectal Cancer (CRC) Screening Among Hispanic Primary Care Patients

RH Genotype Matched RBC Transfusions

Cabazitaxel in Patients With Urothelial Carcinoma Who Have Disease Progression Following Platinum-Based Chemotherapy

Effect of Acetylcysteine With Topotecan Hydrochloride on the Tumor Microenvironment in Patients With Persistent or Recurrent High Grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children

Patient Derived Cancer Cell Lines in Identifying Molecular Changes in Patients With Previously Untreated Pancreatic Cancer Receiving Gemcitabine Hydrochloride-Based Chemotherapy

Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors

Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya

A Study of PF-07260437 in Advanced or Metastatic Solid Tumors

HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients

Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD

A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer