Clinical Trials in Philadelphia

Showing 4321-4340 of 20,904 trials

Enhancing Memory in CPT for PTSD

NCT06000475

Several psychotherapies for posttraumatic stress disorder (PTSD) have a strong evidence base for their efficacy, but nonresponse rates are high, particularly among older Veterans. Accumulating evidence indicates that memory deficits and poor learning of therapy contents adversely affect psychotherapy treatment response in PTSD. However, limited research has examined methods for increasing learning of therapy contents in psychotherapy for PTSD. The proposed study aims to examine the feasibility of integrating an intervention to increase learning and memory of psychotherapy content into the provision of a widely used psychotherapy, cognitive processing therapy (CPT), for older adults with PTSD. The ultimate goal of this line of research is to develop novel rehabilitation interventions to increase functioning for individuals with PTSD.

Stress Disorders, Post-Traumatic

VA Office of Research and Development30 participantsStarted Oct 2024

Philadelphia, Pennsylvania, United States

Active Not RecruitingPhase 2/3< 1 mile

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen

NCT05502341

The goal of this clinical study is to learn more about the effects of switching to the study drugs, bictegravir (BIC) plus lenacapavir (LEN), versus current therapy (Phase 2) and BIC/LEN fixed-dose combination (FDC) versus current therapy (Phase 3) in people living with HIV (PWH).

HIV-1-infection

Gilead Sciences689 participantsStarted Aug 2022

Berkeley, California, United States • Beverly Hills, California, United States • Los Angeles, California, United States +91 more locations

Enhancing Memory in CPT for PTSD

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen

Find Trials by Condition in Philadelphia

CART22 Alone or in Combination With huCART19 for ALL

Next-Generation Photon-Counting CT Technology: Development and Clinical Evaluation

Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

A Study to Evaluate Efficacy and Safety of SAGE-547 in Participants With Severe Postpartum Depression (547-PPD-202B)

Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States

Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) in Subjects With Dim Light Vision Disturbances

Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial

Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors

COVID-19 Study of Pharmacokinetics, Safety, Tolerability, and Efficacy of Intravenous Anti-Spike(s) SARS-CoV-2 Monoclonal Antibodies (Casirivimab+Imdevimab) for the Treatment of Pediatric Patients Hospitalized Due to COVID-19

Role of Aerobic Exercise to Modulate Cardiotoxicity in Long Term Cancer Survivors Exposed to Anthracycline Therapy

RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy

A Study of GSK5733584 in Combination With Anti-cancer Therapies for Advanced Solid Tumors

A Study to Learn About the Occurrence of ADHD in Adults With Mental Conditions and Their Quality of Life

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease