Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
PRIMARY OBJECTIVES:
I. To compare the 30-day overall complication rates between patients with severe obstructive jaundice undergoing preoperative endoscopic biliary drainage with self expanding metal stents (SEMS) and patients undergoing direct surgical resection.
Age
19–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of operable peri-ampullary pancreatic cancer as determined by the Department of Surgery per their standard of care
Serum bilirubin \> 10 mg/dl
Adequate birth control
You may not be if
Patients with evidence of distant metastasis on computed tomography (CT) or magnetic resonance imaging (MRI)
Patients anticipated to require vascular reconstruction
Patients with cholangitis
Patients for whom surgery is deemed inappropriate by surgeon
Patients with bilirubin less than 10 mg/dL or greater than 20 mg/dL
Patients who previously underwent biliary decompression for cholangitis by ERCP or percutaneous transhepatic cholangiography (PTC)
Patients with low performance score (Karnofsky performance status scale \< 50)
Patients with known preexisting liver disease with associated elevated bilirubin
Patients who are pregnant or actively breast feeding
Clareo Health | SEMS Placement Before Surgery in Unblocking Bile Duct in Patients With Periampullary Pancreatic Cancer With Severe Obstructive Jaundice
