Clinical Trials in Philadelphia

Showing 3481-3500 of 15,860 trials

Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis

NCT06578637

The aim of this study is to evaluate the potential of BHB supplementation as a novel strategy to impede the development and progression of intestinal adenomas in individuals with FAP, thus potentially reducing the need for frequent upper endoscopies and colonoscopies and preventing the need for risk-reducing surgical intervention.

FAPFamilial Adenomatous Polyposis

Abramson Cancer Center at Penn Medicine20 participantsStarted Sep 2024

Philadelphia, Pennsylvania, United States

Active Not RecruitingPhase 1< 1 mile

[18F]FLT PET/CT in Rb+ Metastatic Breast Cancer

NCT02608216

In this study positron emission tomography (PET/CT) imaging will be used to evaluate proliferative activity in sites of metastatic disease using the investigational radiotracer \[18F\]fluorothymidine (FLT).

Breast NeoplasmMetastatic Breast CancerRb+ Breast Cancer

University of Pennsylvania20 participantsStarted Nov 2015

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 4< 1 mile

Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention

NCT05207865

The purpose of this study is to further evaluate the long-term safety and tolerability of daily dosing of rimegepant for the prevention of episodic migraine.

MigraineEpisodic MigrainePhonophobia+1 more

Pfizer441 participantsStarted Mar 2022

Phoenix, Arizona, United States • Hawthorne, California, United States • North Hollywood, California, United States +16 more locations

Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis

[18F]FLT PET/CT in Rb+ Metastatic Breast Cancer

Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention

Find Trials by Condition in Philadelphia

Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies

A Phase IIb, Randomized, Double-Blind, Placebo-Controlled Study of Elismetrep (K-304) in the Treatment of Migraine

Strategies and Treatments for Respiratory Infections &Amp; Viral Emergencies (STRIVE): Immune Modulation Strategy Trial

Proton Radiation for Stage II/III Breast Cancer

To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy (LIMBER-213)

Study of 2141-V11 in People With Non-muscle Invasive Bladder Cancer That Did Not Respond to Standard Treatment

Prostate-Specific Membrane Antigen (PSMA) PET Scans in People Prostate Cancer

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis

A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat

Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe Chronic Kidney Disease (CKD)

A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)

A Study of MORAb-202 in Participants With Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC) Adenocarcinoma (AC)

A Study in the United Sates That Looks at the Safety and Effectiveness of Pradaxa Pellets in Children Aged 3 Months to Less Than 12 Years Who Need Treatment of a Blood Clot or Who Have Had a Blood Clot and Are at Risk of Developing Another Blood Clot

Estetrol for the Treatment of Female Sexual Arousal Disorder in Postmenopausal Women

DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia

Sub-study of Belantamab Mafodotin (GSK2857916) as Monotherapy and in Combination With Nirogacestat, Pomalidomide, and Dexamethasone in Participants With RRMM