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Clinical TrialsPhiladelphia

Clinical Trials in Philadelphia

Discover 17,591 clinical trials near Philadelphia, Pennsylvania. Find research studies in your area.

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma Pancreatic Cancer

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 201-220 of 17,591 trials

Active not recruitingTesting GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)This phase II MATCH treatment trial identifies the effects of GDC-0032 (taselisib) in patients whose cancer has a genetic change called PIK3CA mutation.NCT04439175·Philadelphia, Pennsylvania CompletedEvaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU)Prospective, non-randomized, post market clinical evaluation of the VISITAG SURPOINT™ Module with External Processing Unit (EPU) when used with STSF catheter and ST catheter…NCT03624881·Birmingham, Alabama and 40 others

Find Trials by Condition in Philadelphia

Breast Cancerin Philadelphia Lung Cancerin Philadelphia Prostate Cancerin Philadelphia Colorectal Cancerin Philadelphia Melanomain Philadelphia Leukemiain Philadelphia Lymphomain Philadelphia Pancreatic Cancerin Philadelphia Ovarian Cancerin Philadelphia Brain Cancerin Philadelphia

Data from ClinicalTrials.govTerms

CompletedThe Leukotriene Modifier Or Corticosteroid or Corticosteroid-Salmeterol TrialThis research study will compare the treatment effects of three different asthma medications in asthma subjects whose asthma is well controlled when they take fluticasone, an…NCT00156819·Birmingham, Alabama and 18 others

CompletedA Two-Part Multicenter Prospective Longitudinal Study of CFTR-dependent Disease Profiling in Cystic Fibrosis (PROSPECT)identify and validate biomarkers that might reflect partial restoration of CFTR function and can be used to monitor disease progression, and ii) evaluate the mechanistic effects…NCT02477319·Birmingham, Alabama and 37 others

TerminatedSafety and Efficacy of Direct Blood Volume Measurement in the Treatment of Heart FailureHeart failure is a common cardiac condition affecting nearly 6 million Americans.NCT01001312·Honolulu, Hawaii and 8 others

Active not recruitingRadiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE TrialThis phase II trial studies how well radiation therapy with or without apalutamide works in treating patients with prostate cancer that has come back (recurrent).NCT03371719·Gilbert, Arizona and 359 others

TerminatedA Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.The COMMEND Study will assess the safety and effectiveness of FLX-787 in men and women with Motor Neuron Disease \[including Amyotrophic Lateral Sclerosis (ALS), Primary Lateral…NCT03196375·Scottsdale, Arizona and 34 others

CompletedAn Efficacy, Safety and Tolerability Study of Ixmyelocel-T Administered Via Transendocardial Catheter-based Injections to Subjects With Heart Failure Due to Ischemic Dilated Cardiomyopathy (IDCM)This study is designed to assess the efficacy, safety and tolerability of ixmyelocel-T compared to placebo (vehicle control) when administered via transendocardial catheter-based…NCT01670981·Birmingham, Alabama and 35 others

Enrolling by invitationRelationship Between Brain and Heart Glucose Metabolism in Alcohol Use DisorderThe goal of this study is to learn more about how a nutritional supplement "ketone ester" (deltaG ®) has an effect on brain and heart function and on alcohol consumption in…NCT05015881·Philadelphia, Pennsylvania

RecruitingFeasibility of Semaglutide in Advanced Lung DiseaseThe goal of this clinical trial is to learn whether semaglutide, an FDA-approved treatment for diabetes and obesity, is feasible and tolerable in patients with advanced lung…NCT05746039·Philadelphia, Pennsylvania

CompletedRenal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney TxAn open-label, controlled, randomized Phase 3 trial evaluating 12-month kidney function in highly sensitized (cPRA ≥99.9%) kidney transplant patients with positive crossmatch…NCT04935177·Birmingham, Alabama and 24 others

CompletedEfficacy and Safety in Patients With Type 2 Diabetes Mellitus and Cardiovascular DiseaseThis study is carried out to assess whether dapagliflozin improves glycemic control, decreases fasting plasma glucose levels, body weight and blood pressure when added to…NCT01042977·Birmingham, Alabama and 134 others

Active not recruitingPulse-low-dose Rate (PLDR) Radiation in Pancreatic CancerStandard chemoradiation, followed by surgery are standard treatment plan for patients suffering from pancreatic adenocarcinoma.NCT04452357·Philadelphia, Pennsylvania

CompletedStudy to Assess the Efficacy of Larazotide Acetate for the Treatment of Celiac DiseaseThis study was conducted to evaluate the efficacy of multiple doses of larazotide acetate in preventing intestinal permeability changes induced by a 6- week gluten challenge in…NCT00492960·Scottsdale, Arizona and 22 others

UnknownAn Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to RuxolitinibThis is a phase 1b/2 study of KRT-232 combined with ruxolitinib in subjects with MF who have a suboptimal response after at least 18 weeks of treatment with ruxolitinib.NCT04485260·Duarte, California and 37 others

Active not recruitingA Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AMLThis study will evaluate the safety, efficacy and pharmacokinetics of midostaurin in combination with standard chemotherapy in pediatrics patients with newly diagnosed…NCT03591510·Prague and 14 others

TerminatedTelehealth Based Synchronous Navigation to Improve Molecularly-Informed Care for Patients With Lung CancerThe goal of this trial is to design and test a telehealth nurse navigation intervention for patients with suspected locally advanced/metastatic NSCLC to improve timely…NCT05790460·Philadelphia, Pennsylvania

TerminatedPhase III Trial to Investigate Efficacy and Safety of Vilobelimab in Ulcerative Pyoderma GangrenosumA randomized, double-blind, placebo-controlled, multicenter, adaptive phase III trial to investigate efficacy and safety of vilobelimab in the treatment of ulcerative pyoderma…NCT05964413·Hialeah, Florida and 49 others

CompletedPostoperative Analgesia After Shoulder ReplacementA comparison was made regarding opioid analgesic usage immediately after elective shoulder replacement and for seven days at home between patients randomly given either 0.5% or…NCT01003860·Philadelphia, Pennsylvania

CompletedA Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in Participants With IgANThis was a 28-week, open-label, multicenter, single-group Phase 2 exploratory study to determine the safety and effect of sparsentan in participants with IgAN who are at risk of…NCT05856760·Birmingham, Alabama and 29 others

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