Clinical Trials in Ohio

Showing 6121-6140 of 20,938 trials

Evaluation of Carboplatin/Paclitaxel/Bevacizumab in the Treatment of Advanced Stage Endometrial Carcinoma

NCT00513786

Purpose of this study is to determine the effectiveness of the drug combination carboplatin, paclitaxel, and bevacizumab(Avastin) in patients with advanced stage endometrial carcinoma.

Endometrial Cancer

David O'Malley38 participantsStarted Aug 2007

Columbus, Ohio, United States

COMPLETEDPhase 132 miles

Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

NCT04761614

This phase I trial is to find out the best dose, possible benefits, and/or side effects of riluzole and how well it works in combination with standard of care mFOLFOX6 and bevacizumab in treating patients with colorectal cancer that has spread to other places in the body (metastatic). Riluzole is a well-tolerated oral medication that has demonstrated it may make chemotherapy work better. Chemotherapy drugs, such as oxaliplatin, leucovorin calcium and fluorouracil, work in different ways to stop the growth of \[cancer/tumor\] cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Bevacizumab is an antibody that targets the blood vessel by blocking the activity of a protein called vascular endothelial growth factor alpha (VEGF-A). It helps to make the mFOLFOX6 more effective. Giving riluzole, mFOLFOX6, and bevacizumab may kill more tumor cells compared to mFOLFOX6 and bevacizumab alone in treating patients with colorectal cancer.

Metastatic Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8Stage IVA Colorectal Cancer AJCC v8+2 more

Ning Jin13 participantsStarted Apr 2021

Columbus, Ohio, United States

Evaluation of Carboplatin/Paclitaxel/Bevacizumab in the Treatment of Advanced Stage Endometrial Carcinoma

Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Find Trials by Condition in Ohio

Epidural Fentanyl for 2nd Stage Labor Analgesia

A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention

Opioid Consumption in Cystectomy Patients

MIP Versus PCNL for Kidney Stone Disease

Sunitinib Malate in Treating Patients With Thyroid Cancer That Did Not Respond to Iodine I 131 and Cannot Be Removed by Surgery

Targeting Resistant Prostate Cancer With ATR and PARP Inhibition (TRAP Trial)

Detection and Classification of Cardiac Rhythm and Atrial Fibrillation Using a Finger-worn Ring

Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey

Long-term Study of Semapimod (CNI-1493) for Treatment of Crohn's Disease

Noninvasive Monitoring of Uterine Activity and Fetal Heart Rate

Kids FACE FEARS Comparative Effectiveness Research

Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.

Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome

Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer

Vitamin D to ENhance TraUma REcovery

Walking and mHealth to Increase Participation in Parkinson Disease

A Bioequivalence Study of Mirikizumab (LY3074828) Solution in Healthy Participants

Efficacy of Emotionally Focused Therapy Among Spanish Speaking Couples