Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Naurex, Inc, an affiliate of Allergan plc
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Meet Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5) criteria for MDD
Current major Depressive episode of at least 4 weeks and not exceeding 24 months in duration at visit 1
Have current, ongoing suicidality (ideation or behavior) of sufficient severity to warrant hospitalization based on the judgment of the investigator
If female of childbearing potential, have a negative serum β-human chorionic gonadotropin (β-hCG) pregnancy test.
You may not be if
DSM-5-based diagnosis of any disorder other than MDD that was the primary focus of treatment within 1 month before Visit 1.
Lifetime history or currently meet DSM-5 criteria for:
1. Schizophrenia spectrum or other psychotic disorder
2. Bipolar or related disorder
3. Major neurocognitive disorder
4. Neurodevelopmental disorder of greater than mild severity or of a severity that impacts the participant's ability to consent, follow study directions, or otherwise safely participate in the study.
5. Dissociative disorder
6. Posttraumatic stress disorder
7. MDD with psychotic features
Significant homicidal ideation or at imminent risk of injuring others or causing significant damage to property, as judged by the investigator.
Prior participation in any investigational study of rapastinel/GLYX-13
