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Clinical Trials in Ohio | 20,938 Studies Near You | Clareo Health

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Clinical Trials in Ohio

Discover 20,938 clinical trials near Ohio. Find research studies in your area.

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Showing 4641-4660 of 20,938 trials

TERMINATEDPhase 232 miles

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Ichthyosis

NCT04697056

Efficacy and Safety of imsidolimab in Participants with Ichthyosis

Vanda Pharmaceuticals5 participantsStarted Jan 2021

Palo Alto, California, United States • New Haven, Connecticut, United States • Miami, Florida, United States +4 more locations

TERMINATEDPhase 232 miles

A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery

NCT05814016

The main aim is to see if danavorexton can help improve people's breathing in the recovery room after abdominal surgery.

Takeda41 participantsStarted May 2023

Sheffield, Alabama, United States • Phoenix, Arizona, United States • La Jolla, California, United States +16 more locations

Find Trials by Condition in Ohio

Breast Cancerin Ohio Lung Cancerin Ohio Prostate Cancerin Ohio Colorectal Cancerin Ohio Melanomain Ohio Leukemiain Ohio Lymphomain Ohio Pancreatic Cancerin Ohio Ovarian Cancerin Ohio Brain Cancerin Ohio Diabetesin Ohio

Data from ClinicalTrials.govTerms

COMPLETEDNA32 miles

The Use of Mentoring to Promote Well-being for Female SMART Members

NCT04247880

Women are highly underrepresented in the construction skilled trades. In addition to facing the industry's well-known physical risks, women are subjected to discrimination, harassment, and skills under-utilization. As a result, tradeswomen have increased risk for injury, stress-related health effects, and high attrition rates from apprenticeship programs, thus perpetuating their minority status. Mentoring is a well-established technique for learning technical and personal navigation skills in new or challenging social environments. The investigators propose development and dissemination of a mentorship program through local unions of the International Association of Sheet Metal, Air, Rail and Transportation Workers (SMART), and evaluating its success in reducing women's injury and work stress, while improving retention.

Harassment, Non-SexualHarassment, SexualBullying, Workplace+4 more

University of Washington96 participantsStarted Mar 2021

Phoenix, Arizona, United States • Glendora, California, United States • San Jose, California, United States +16 more locations

COMPLETEDPhase 332 miles

Safety Study of a Vaccine to Help Protect Against Lyme Disease in Healthy Children

NCT05634811

This study is to understand if the study vaccine (called VLA15) is safe in healthy children. We are looking for children who: * are healthy * are age 5 through 17 * have not been diagnosed with any form of Lyme disease in the past * have not received any vaccines for Lyme disease in the past Lyme disease happens most often in children of this age. The study vaccine may be used potentially to help prevent Lyme disease. The goal of this study is to get more information about the safety of the study vaccine in this age group. Participants will be in this study for about 2 years. During that time, they will receive VLA15 or placebo (sterile saltwater solution) by a "shot" in the arm. We will compare experience of children receiving VLA15 to those receiving the placebo. Participants will not know whether they get VLA15 or placebo. Everyone participating in this study will: * get the shots in a clinic or in a hospital office * receive a total of 4 shots * receive the first 3 shots within 6 months * receive the last shot about 1 year afterwards * need to come to the trial site for 6 planned visits; 4 of these are vaccination visits and 2 are follow-up visits. We will contact you by phone 1 time every year during the study to monitor your experience. You may have extra visits if you experience a severe reaction after a vaccine dose.

Pfizer3,549 participantsStarted Dec 2022

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Guntersville, Alabama, United States +62 more locations

COMPLETEDPhase 297 miles

A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)

NCT05107128

The primary purpose of this study is to evaluate the effect of SAGE-718 on cognitive performance and functioning in participants with HD.

Huntington's Disease

Supernus Pharmaceuticals, Inc.189 participantsStarted Jan 2022

Little Rock, Arkansas, United States • La Jolla, California, United States • Los Angeles, California, United States +46 more locations

COMPLETEDPhase 1127 miles

Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older

NCT05426174

This is a Phase I, first-in-human, randomized, modified double-blind, active-controlled, dose-escalation study to assess the safety and immunogenicity of up to 3 dose levels of mRNA NA vaccines, administered as a single IM injection in healthy adults aged 18 years and older. Two age groups, 18 to 64 years and ≥65 years, will be included in this study.

Influenza ImmunizationHealthy Volunteers

Sanofi Pasteur, a Sanofi Company233 participantsStarted Jun 2022

Huntsville, Alabama, United States • Phoenix, Arizona, United States • San Diego, California, United States +3 more locations

Active Not RecruitingNA135 miles

Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

NCT00819208

RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical fitness, psychological well-being and the quality of life of patients who have undergone surgery and chemotherapy for colon cancer. It is not yet known whether giving a physical activity program together with health education materials is more effective than giving health education materials alone for patients who have undergone colon cancer treatment. PURPOSE: This randomized phase III trial is studying a physical activity program given together with health education materials to see how well it works compared with giving health education materials alone for patients who have undergone treatment for high-risk stage II or stage III colon cancer.

Anxiety DisorderCognitive/Functional EffectsColorectal Cancer+5 more

Canadian Cancer Trials Group889 participantsStarted Jun 2009

Detroit, Michigan, United States • Lebanon, New Hampshire, United States • Chapel Hill, North Carolina, United States +44 more locations

COMPLETEDNA140 miles

sipIT2: Improving Adherence to Fluid Intake Guidelines for Kidney Stone Prevention

NCT05196113

The purpose of this study is to examine the feasibility of using sipIT tools (i.e., wrist-worn sensors, smart water bottles, mobile applications) to increase compliance with physician-recommended fluid consumption guidelines in participants with a history of urolithiasis.

University of Michigan216 participantsStarted Jan 2022

Ann Arbor, Michigan, United States • Hershey, Pennsylvania, United States

RECRUITING140 miles

DFC 004 Biomarkers for Active Diabetic Foot Ulcers

NCT06104969

This study is a platform study designed to efficiently test multiple biomarkers to identify diabetic foot ulcers (DFUs) with a higher potential for healing versus not healing that ultimately could be applied at the point of care to drive personalized management decisions, and to better inform clinical trials of wound healing interventions

Diabetic Foot UlcerDiabetic FootDiabetes

University of Michigan5,000 participantsStarted Jun 2023

Tucson, Arizona, United States • Los Angeles, California, United States • San Francisco, California, United States +5 more locations

RECRUITINGPhase 1/2146 miles

Promising ROd-cone DYstrophy Gene therapY

NCT05748873

This is a two-step, multicenter, Phase I/II study including an open-label dose-escalation phase (Step 1) and a three-arm, controlled, double-masked, randomized extension phase (Step 2), in subjects with advanced RCD due to a mutation in the RHO, PDE6A, or PDE6B gene.

Retinitis Pigmentosa

SparingVision33 participantsStarted Apr 2023

Miami, Florida, United States • Boston, Massachusetts, United States • Portland, Oregon, United States +3 more locations

COMPLETEDNA151 miles

Device for Improving Skin Quality and Texture on the Face and Neck

NCT06645366

The goal of this clinical trial is to investigate the effect of the BTL-785F device (with BTL-785-4-4 tip on BTL-785-4 applicator) on the improvement of skin quality and texture on the face and neck in healthy adult volunteers. The main question it aims to answer is: Whether the BTL-785F device (with BTL-785-4-4 tip on BTL-785-4 applicator) is able to improve skin quality 3 months post-treatment, as assessed by two-dimensional and three-dimensional photographs. Participants will complete three treatments, and two follow-up visits.

WrinklePigmentationSkin Laxity+1 more

BTL Industries Ltd.39 participantsStarted Jun 2024

Greenwood Village, Colorado, United States • Chevy Chase, Maryland, United States • Birmingham, Michigan, United States

Active Not Recruiting158 miles

Real-World Effectiveness of Dupilumab in Patients With Prurigo Nodularis: An Observational Study

NCT05991323

This study is a prospective, multinational, observational investigation designed to elucidate the real-world effectiveness and treatment patterns of dupilumab therapy in adult patients diagnosed with prurigo nodularis (PN). The primary objective of this study is to comprehensively characterize the real-world usage of dupilumab for the management of PN. In addition to this, the study aims to achieve several secondary objectives, including a detailed assessment of the medical history, socio-demographic and disease characteristics of dupilumab-treated PN patients, as well as the evaluation of the long-term real-world effectiveness of dupilumab therapy for PN.

Prurigo Nodularis

Sanofi100 participantsStarted Dec 2023

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Fremont, California, United States +46 more locations

TERMINATEDPhase 1/2233 miles

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

NCT04278144

A first-in-human study using BDC-1001 as a single agent and in combination with nivolumab in HER2 expressing advanced malignancies

HER2-positive Solid TumorsHER2-positive Breast CancerHER2-positive Colorectal Cancer+2 more

Bolt Biotherapeutics, Inc.175 participantsStarted Feb 2020

Palo Alto, California, United States • Washington D.C., District of Columbia, United States • Chicago, Illinois, United States +18 more locations

COMPLETEDPhase 2/3274 miles

PRO 140 in Treatment-Experienced HIV-1 Subjects

NCT03902522

The primary objectives of the trial are to assess the efficacy, clinical safety and tolerability parameters of PRO 140 in combination with failing ART (antiretroviral therapy) during the initial one-week treatment period, and in combination with Optimized Background Therapy during the subsequent 24-week treatment period.

HIV-1-infection

CytoDyn, Inc.6 participantsStarted Jun 2018

Palm Springs, California, United States • San Francisco, California, United States • New Haven, Connecticut, United States +14 more locations

COMPLETEDNA280 miles

Omnipod 5 System Compared to Pump Therapy

NCT05409131

Subject will undergo a 14-day outpatient, standard therapy phase during which sensor and insulin data will be collected. This will be followed by a 90-day outpatient phase where subjects will either use the Omnipod 5 system or continue to use their personal insulin pump with the study provided continuous glucose monitoring system. Participants in France will be offered an optional extension of 12 months of Omnipod 5 System use.

Type 1 Diabetes

Insulet Corporation196 participantsStarted Jul 2022

Palo Alto, California, United States • Santa Barbara, California, United States • Denver, Colorado, United States +11 more locations

COMPLETEDNA307 miles

BlueWind RENOVA iStim™ System for the Treatment of OAB

NCT03596671

The OASIS study is prospective, interventional, multi-center study to evaluate the safety and efficacy of the BlueWind RENOVA iStim™ implantable tibial neuromodulation System for the treatment of patients diagnosed with overactive bladder.

Treatment of Patients Suffering From Overactive Bladder (OAB)

BlueWind Medical282 participantsStarted Jun 2019

Orange, California, United States • San Diego, California, United States • Norwalk, Connecticut, United States +20 more locations

COMPLETED309 miles

Locking Plates for Distal Femur Fractures - a Multicenter Case Review

NCT04008940

In order to assess the rate and mode of failure cases observed in patients with distal femur fractures treated with a distal femur plates, anonymized radiographs from those patients will be collected retrospectively. All available images will reviewed by an expert review board in regards to fracture classification, implant and surgery details, quality of initial reduction and plate positioning as well as the occurrence of mechanical complications and the outcome in terms of fracture healing (if available). Additionally, age and gender as basic demographical data will be collected in a de-identified way..

Distal Femur Fracture

AO Innovation Translation Center100 participantsStarted Jan 2012

Sacramento, California, United States • Houston, Texas, United States • Fairfax, Virginia, United States +2 more locations

COMPLETEDPhase 2322 miles

Study of Anti-Malarials in Incomplete Lupus Erythematosus

NCT03030118

This project is a multicenter, randomized, placebo-controlled, double-blind clinical trial that is designed to test whether treating patients who are at risk for development of lupus with hydroxychloroquine can slow accumulation of disease features. Effects on clinical progression of symptoms, patient-reported outcomes and changes in the immune markers of response will be measured and toxicity of the treatment will be assessed. This trial is a first step in testing a prevention strategy for lupus.

Systemic Lupus Erythematosus

Milton S. Hershey Medical Center187 participantsStarted Dec 2017

Los Angeles, California, United States • Aurora, Colorado, United States • Great Neck, New York, United States +4 more locations

COMPLETEDNA465 miles

Veterans Response to Dosage in Chiropractic Therapy

NCT04087291

This study evaluates how Veterans with chronic low back pain (cLBP) respond to varying doses of chiropractic therapy and how health services utilization are impacted as a result. There are 2 phases in this study. In Phase 1, half of participants will receive a low dose (1-5 visits) of chiropractic care for 10 weeks, while the other half will receive a higher dose (8-12 visits) for 10 weeks. At the end of Phase 1, participants in each group will be randomized again to receive either chronic chiropractic pain management (CCPM) (1 scheduled chiropractic visit per month x 10 months) or no CCPM for 10 months.

Low Back PainPatient Acceptance of Health CareVeterans Health

Palmer College of Chiropractic766 participantsStarted Feb 2021

Los Angeles, California, United States • West Haven, Connecticut, United States • Iowa City, Iowa, United States +1 more locations

COMPLETEDPhase 41173 miles

Dupilumab-PEdiatric Skin Barrier Function and LIpidomics STudy in Patients With Atopic Dermatitis

NCT04718870

Primary Objective: \- Evaluate changes in skin barrier function with transepidermal water loss (TEWL) assessed after skin tape stripping (STS) in predefined lesional skin in pediatric participants with moderate to severe atopic dermatitis (AD) treated with dupilumab. Secondary Objectives: * Evaluate changes in skin barrier function with TEWL assessed after STS in predefined lesional and non-lesional skin in pediatric participants with moderate to severe AD treated with dupilumab in reference to normal skin of healthy volunteers. * Evaluate time course of change in skin barrier function with TEWL assessed before and after STS in predefined lesional and non-lesional skin in pediatric participants with moderate to severe AD during dupilumab treatment phase and follow-up period in reference to normal skin of healthy volunteers.

Dermatitis Atopic

Sanofi41 participantsStarted Feb 2021

Los Angeles, California, United States • Denver, Colorado, United States • Sheffield, United Kingdom

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