Clinical Trials in Ohio

Showing 4081-4100 of 15,929 trials

A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region

NCT05789576

This is an open-label, multi-center study to evaluate the efficacy and safety of VTAMA (tapinarof) cream, 1% in adults with plaque psoriasis occurring in the head and neck region

Psoriasis

Organon and Co31 participantsStarted Mar 2023

Macon, Georgia, United States • Chicago, Illinois, United States • Rockville, Maryland, United States +7 more locations

COMPLETEDNA32 miles

Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese Adults

NCT03413735

This study is focused on assessing gastrointestinal-level improvements by which green tea limits metabolic endotoxemia. It is completed in two phases. Phase I consists of a pharmacokinetic study to examine the bioavailability of green tea catechins among lean and obese persons who consumed a single dose of a green tea extract (GTE)-containing confection. These persons will then complete phase 2, which consists of a parallel design randomized controlled in which lean and obese persons will consume placebo or GTE confections. It is expected that catechin-rich green tea will improve gut barrier function to prevent endotoxin translocation and associated low-grade inflammation. Outcomes will therefore support dietary recommendations for green tea to alleviate obesity-related inflammatory responses. Specifically, the study is expected to demonstrate that a green tea confection snack food can attenuate metabolic endotoxemia in association with restoring gastrointestinal health.

ObesityEndotoxemiaInflammation

Ohio State University40 participantsStarted Aug 2018

Columbus, Ohio, United States

A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region

Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese Adults

Find Trials by Condition in Ohio

Shared-Decision Making for Hydroxyurea

Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy

ALL Adult Consortium Trial: Adult ALL Trial

A Study to Evaluate the Efficacy and Safety of Gantenerumab in Participants at Risk for or at the Earliest Stages of Alzheimer's Disease (AD)

Intravitreal ERT to Prevent Retinal Disease Progression in Children With CLN2

Tolerability and Immunogenicity of a Single 40-ug Dose of rBV A/B for the Production of BabyBIG®

A Phase 1 Study of NM6603 in Advanced Solid Tumors

Tapinarof for the Treatment of Plaque Psoriasis in Adults (3001)

Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

Natural History Study of Synucleinopathies

An Evaluation of the Safety of CSF-1 in Presbyopic Subjects

A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis

AVID100 in Advanced Epithelial Carcinomas

A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes

Long-Term Safety and Antibody Persistence of TDV and the Impact of a Booster Dose

AZD3470 as Monotherapy and in Combination With Anticancer Agents in Participants With Relapsed/Refractory Haematologic Malignancies.

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease