Clinical Trials in Ohio

Showing 3381-3400 of 17,983 trials

Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

NCT06377488

This will be an open-label, 3-visit, single-arm, dispensing clinical trial to evaluate visual acuity.

Johnson & Johnson Vision Care, Inc.176 participantsStarted Apr 2024

Jacksonville, Florida, United States • Jacksonville, Florida, United States • Longwood, Florida, United States +12 more locations

COMPLETEDPhase 232 miles

Bortezomib After Combination Chemotherapy, Rituximab, and an Autologous Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

NCT00310037

This randomized phase II trial studies how well bortezomib works when given after combination chemotherapy, rituximab, and an autologous stem cell transplant in treating patients with mantle cell lymphoma. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) together with an autologous stem cell transplant may allow more chemotherapy to be given so that more cancer cells are killed. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Giving bortezomib after combination chemotherapy, monoclonal antibody therapy, and an autologous stem cell transplant may kill any remaining cancer cells or keep the cancer from coming back.

Mantle Cell Lymphoma

Alliance for Clinical Trials in Oncology151 participantsStarted Jun 2006

San Francisco, California, United States • Bloomington, Illinois, United States • Bloomington, Illinois, United States +45 more locations

Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

Bortezomib After Combination Chemotherapy, Rituximab, and an Autologous Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

Find Trials by Condition in Ohio

Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemia

A Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With Chemotherapy Compared With Pembrolizumab in Combination With Chemotherapy in Metastatic NSCLC Patients With Non-squamous Histology Who Have Mutations and/or Co-mutations in STK11, KEAP1, or KRAS

Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02)

Changes in Cerebral Oxygenation Related to Intraoperative Position Changes

Selexipag (ACT-293987) in Pulmonary Arterial Hypertension

Phase 2b Study of GSK4532990 in Adults With NASH

A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)

Gadopiclenol Pharmacokinetics, Safety and Efficacy in Children < 2 Years of Age

Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy

A Study of XMT-1660 in Participants With Solid Tumors

Efficacy and Safety of Deucravacitinib Versus Placebo in Participants With Moderate-to-severe Scalp Psoriasis

Safety and Effectiveness Study of OR3O™ Dual Mobility System in THA

A Clinical Trial to Investigate Long-term Safety, Tolerability, and Efficacy of Weekly Subcutaneous Doses With TransCon CNP in Children and Adolescents With Achondroplasia

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

Pediatric Patients Aged 4 to 11 Years With APDS

Improving Risk Assessment of AML With a Precision Genomic Strategy to Assess Mutation Clearance

Evaluating the Association Between Changes in the Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Breast Cancer

Stryker's Surgeon iD Mandible Reconstruction Plates: A Retrospective Post Market Follow Up