Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Acorda Therapeutics
Age
30–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Idiopathic Parkinson's Disease (PD) diagnosed between the ages of 30 and 85 years;
Hoehn and Yahr Stage 1-3 in an "on" state;
Require levodopa-containing medication regimen at least 3 times during the waking day;
Experience motor fluctuations with a minimum of 2 hours of average daily "off" time per waking day (excluding early morning "off" time) and demonstrate levodopa responsiveness;
Are on stable PD medication regimen;
Total daily LD dose \<1600 mg/day;
Able to perform a spirometry maneuver in the ON and OFF states;
Normal cognition confirmed by MMSE score ≥25
You may not be if
Pregnant or lactating females;
Previous surgery for PD or plan to have stereotactic surgery during the study period;
History of psychotic symptoms requiring treatment, or suicide ideation or attempt within last year;
Known contraindication to the use of levodopa;
Any significant condition, severe concurrent disease, abnormality or finding that would make patients unsuitable or may compromise patient safety;
Any contraindication to performing routine spirometry.
