Clinical Trials in Nashville

Showing 18801-18820 of 20,298 trials

Evaluation of Consistency of StaphVAX Manufacturing Lots

NCT00211991

This study answers a U.S. Food and Drug Administration requirement for evaluation in people of the consistency of manufacturing of a vaccine. Subjects are randomized to one of three lots of vaccine. The antibodies in the blood measure the immunogenicity of each lot of vaccine, and typical vaccine safety information is also collected.

Staphylococcal Infections

Nabi Biopharmaceuticals354 participantsStarted Apr 2005

Nashville, Tennessee, United States

COMPLETEDPhase 4< 1 mile

Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome

NCT00666848

This study will measure the effect of the anti-diabetic agent sitagliptin on blood pressure in individuals with the metabolic syndrome. We will also measure the effect of sitagliptin on blood pressure in people already taking a blood pressure medication called an ACE inhibitor.

Metabolic SyndromeHypertension

Vanderbilt University24 participantsStarted Mar 2008

Nashville, Tennessee, United States

TERMINATEDPhase 1< 1 mile

A Phase I Study of the Oral Platinum Agent Satraplatin in Combination With Weekly Docetaxel

NCT00313456

This is a single-center, open-label (sequential-group dose-escalation dose-finding) phase I study of satraplatin and docetaxel in patients who have received prior chemotherapy regimens. Once the MTD is determined, an additional 6 patients, all with chemotherapy-naïve HRPC, will be enrolled. Once a recommended dose(s) (RD(s)) for phase 2 studies has/have been determined, 6 additional patients with chemotherapy-naïve HRPC will be enrolled at the RD to further evaluate safety and efficacy.

TumorsProstate Cancer

Agennix25 participantsStarted Mar 2006

Nashville, Tennessee, United States

Evaluation of Consistency of StaphVAX Manufacturing Lots

Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome

A Phase I Study of the Oral Platinum Agent Satraplatin in Combination With Weekly Docetaxel

Find Trials by Condition in Nashville

FACTS II: A Study to Test the Safety and Effectiveness of a New Medication on the Treatment of Active Ulcerative Colitis

PTK787 in Patients With Advanced Metastatic Pancreatic Adenocarcinoma

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus COPEGUS (Ribavirin) With or Without Pioglitazone in Treatment-Naive Patients With Chronic Hepatitis C and Insulin Resistance.

Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-340)

HIV Resistance and Treatment Strategies

Heart Pressure Assessment Study With Tolvaptan to Treat Congestive Heart Failure

Randomized Study of Anular Repair With the Xclose Tissue Repair System

Study of the Safety and Efficacy of Apadenoson for Detection of Myocardial Perfusion Defects Using SPECT MPI

Safety Study of AMI MultiStem® to Treat Heart Attacks

Suramin Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Evaluating the Ability of Zoledronic Acid to Reduce the Rate of Subsequent Osteoporotic Fractures After a Hip Fracture

Safety and Efficacy Study of CEP-1347 in the Treatment of Parkinson's Disease

A Noninvasive Test for Fetal RHD Genotype

Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period

First-in-human Study of AB0024 to Evaluate Safety and Tolerability in Adults With Advanced Solid Tumors

Dose Finding Posterolateral Thoracotomy Study

Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma