Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-340)

Exclusion Criteria

• •Acute peptic ulcer and/or ulcer complications
• •Systemic glucocorticoids or non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2-inhibitors on more than 3 consecutive days within the previous 28 days; except regular intake of acetylsalicylic acid in dosages up to 163 mg/day
• •Intake of Proton Pump Inhibitors and Histamine 2-receptor antagonists within the previous 14 days
• •Intake of psychotropic medication, dyspepsia-inducing drugs, and anticholinergic agents
• •Pregnant or nursing female patients; Non-pregnant, non-lactating female patients of childbearing potential who are not using reliable method of contraception