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Clareo Health | Colorectal Cancer Clinical Trials in Nashville | 359 Studies

Clinical Trials Colorectal CancerNashville

Colorectal Cancer Clinical Trials in Nashville

Find 359 clinical trials for colorectal cancer near Nashville, Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Nashville

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 1-20 of 359 trials

Active not recruitingStudy of JANX008 in Subjects With Advanced or Metastatic Solid Tumor MalignanciesThis study is a first-in-human (FIH), Phase 1/1b, open-label, multicenter dose escalation and dose expansion study to assess the safety, tolerability, pharmacokinetics (PK)…NCT05783622·Duarte, California and 17 others CompletedPhase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial TumorsThis is a Phase I multicenter, open label, nonrandomized study of enadenotucirev administered in combination with nivolumab in subjects with metastatic or advanced epithelial…NCT02636036·Tucson, Arizona and 5 others

Colorectal Cancer Trials in Other Cities

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Data from ClinicalTrials.govTerms

TerminatedSequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal CancerThis randomized, open-label, multicenter study will evaluate the efficacy and safety of folinic acid (leucovorin), 5-fluorouracil (5-FU), oxaliplatin, and irinotecan (FOLFOXIRI) /…NCT01765582·Mobile, Alabama and 44 others

CompletedPrograms To Support You During ChemotherapyThis randomized pilot trial studies how well two supportive programs work for improving fatigue and depressive symptoms in patients with GI undergoing chemotherapy.NCT02489422·Winston-Salem, North Carolina and 1 other

CompletedPhase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal CancerThis phase 1/2, multi-center, randomized, double-blind, placebo-controlled trial is designed to evaluate the efficacy and safety of AMG 655 when combined with mFOLFOX6 and…NCT00625651·Hot Springs, Arkansas and 60 others

SuspendedA Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid TumorsThis is a first in human, single arm, open label, Phase 1a/1b study to determine the safety, feasibility, and efficacy of a single dose of NeoTCR-P1 T cells in participants with…NCT03970382·Duarte, California and 8 others

UnknownA Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid TumorsThis is a study of navicixizumab monotherapy or in combination with paclitaxel or irinotecan in patients with advanced cancer.NCT05453825·Hot Springs, Arkansas and 7 others

TerminatedStudy of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid TumorsThis study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene…NCT04383210·Birmingham, Alabama and 41 others

Active not recruitingA Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X MutationsTo evaluate the efficacy of naporafenib administered with trametinib in patients with rat sarcoma viral oncogene (RAS) Q61X solid tumors * To evaluate the safety and tolerability…NCT05907304·San Francisco, California and 28 others

CompletedOxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With SurgeryPURPOSE: This randomized phase III trial is studying giving oxaliplatin, leucovorin calcium, and fluorouracil together to compare how well they work when given together with or…NCT01150045·Mobile, Alabama and 841 others

TerminatedTovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid TumorsThis is a Phase 2, multi-center, open-label to evaluate the efficacy and safety of tovorafenib (DAY101) in participants ≥12 years of age with recurrent or progressive melanoma or…NCT04985604·Los Angeles, California and 19 others

CompletedA Study of PDR001 in Combination With CJM112, EGF816, Ilaris® (Canakinumab) or Mekinist® (Trametinib)The purpose of this study was to combine the PDR001 checkpoint inhibitor with each of four agents with immunomodulatory activity to identify the doses and schedule for combination…NCT02900664·Baltimore, Maryland and 22 others

TerminatedA Study to Learn About PF-07921585 Alone or With Other Anti-cancer Medicines in People With CancerThe purpose of this study is to learn about the safety and effects of the study medicine (called PF-07921585) in people with cancer that has advanced or spread to other parts of…NCT06580938·Fayetteville, Arkansas and 8 others

CompletedGrowth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial CancerRATIONALE: Measuring levels of transforming growth factor-beta (TGF-beta) in the blood of patients with epithelial cancers (head and neck, lung, breast, colorectal, and prostate)…NCT00897793·Nashville, Tennessee and 2 others

Active not recruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid TumorsThis is a first-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of enzelkitug when administered as a single agent and in…NCT05581004·San Francisco, California and 31 others

TerminatedStudy of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D MutationA Phase 1/2 study of MRTX1133 in solid tumors harboring a KRAS G12D mutation.NCT05737706·Phoenix, Arizona and 13 others

CompletedStudy of NK012 and 5-FU/LV in Solid Tumors Followed by Dose Expansion in Colorectal CancerThe primary objective is to determine the maximum tolerated dose/recommended phase II dose of the combination regimen of NK012 and 5-fluorouracil in patients with advanced solid…NCT01238939·Nashville, Tennessee

Active not recruitingA Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid TumorsThe main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally advanced or metastatic solid…NCT06607185·Birmingham, Alabama and 44 others

CompletedA Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer TreatmentThis is a three-part study of NUC-3373 administered by intravenous (IV) infusion across two administration schedules, either as monotherapy or as part of various combinations with…NCT03428958·Boston, Massachusetts and 9 others

Not yet recruitingA Study of CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101)Phase 1, open-label, multicenter study to evaluate the safety, tolerability, PK, PD, and preliminary clinical activity of CLSP 5282 when administered to HLA A\*03:01-positive…NCT07650357·Durham, North Carolina and 3 others

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