Clinical Trials in Massachusetts

Showing 4221-4240 of 15,316 trials

A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans

NCT03489122

The proposed study addresses a gap regarding the need for effective Major Depressive Disorder (MDD) treatments and the 40% of individuals treated with antidepressant medications that do not achieve full remission. This study tests a novel approach for treating MDD in a Randomized Control Trial (RTC) using yoga versus walking interventions to correct an imbalance in the Autonomic Nervous System; an over active Sympathetic Nervous System (fight or flight) an underactive Parasympathetic Nervous System (PNS) (rest, renewal and social engagement) and associated under activity in the neurotransmitter, gamma aminobutyric acid (GABA). This novel approach is complimentary to the use of antidepressant medications that primarily target the monoamine systems. Low activity in the PNS and GABA systems are also found in MDD, PTSD, and Alcohol Use Disorder, disorders representing a high healthcare burden in the Veteran population. This intervention has potential to provide relief for MDD and other disorders relevant the Veteran population

Depressive Disorder, MajorPost Traumatic Stress Disorder

VA Office of Research and Development2 participantsStarted Jan 2022

Bedford, Massachusetts, United States

Active Not Recruiting26 miles

Impairments That Affect Correct Inhaler Use in COPD

NCT06135324

INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: 1. Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic obstructive pulmonary disease (COPD). 2. Assess the relationship of cognitive impairment and impaired manual dexterity with patient errors using current pMDIs, SMIs and/or DPIs.

COPD

COPD Foundation500 participantsStarted Dec 2023

Birmingham, Alabama, United States • Chicago, Illinois, United States • Burlington, Massachusetts, United States +6 more locations

A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans

Impairments That Affect Correct Inhaler Use in COPD

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HEALEY ALS Platform Trial - Regimen E SLS-005 - Trehalose

This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 Year

Pediatric ACL: Understanding Treatment Options

Regorafenib Plus Pembrolizumab in Patients With Advanced or Spreading Liver Cancer Who Have Been Previously Treated With PD-1/PD-L1 Immune Checkpoint Inhibitors

Phase I/II Trial of Alectinib and Bevacizumab in Patients With Advanced, Anaplastic Lymphoma Kinase (ALK)-Positive, Non-Small Cell Lung Cancer

A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery

Lenalidomide (Revlimid®, CC-5013) in Subjects With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma

PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study

Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

Exercise to Augment TMS in Those With Treatment Resistant Depression

Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hysterectomy

Synchronous vs Asynchronous Remotely Delivered Lifestyle Interventions

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

REC 0/0559 Eye Drops for Treatment of Moderate and Severe Neurotrophic Keratitis in Adult Patients

STEM-Parkinson's Disease

Adalimumab in JIA-associated Uveitis Stopping Trial

A Study to Assess Adverse Events and Change in Disease Activity of HArmonyCa Lidocaine Injectable Gel for Mid Face Soft Tissue Augmentation in Adult Participants