Clinical Trials in Massachusetts

Showing 4241-4260 of 15,316 trials

Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

NCT05970562

Vocal hyperfunction (VH) is the most commonly treated class of voice disorders by speech-language pathologists and voice therapy is the primary curative treatment. Patients and clinicians report that generalizing improved voicing into daily life is the most significant barrier to successful therapy. We will test if extending biofeedback into the patient's daily life using ambulatory voice monitoring will significantly improve generalization during therapy and if individual patient factors, like how easily they can modify their voice and engagement during therapy, moderate the effects of the biofeedback.

Voice DisordersVocal Fold PolypVocal Nodules in Adults+1 more

Massachusetts General Hospital100 participantsStarted Mar 2024

Boston, Massachusetts, United States • Boston, Massachusetts, United States

Active Not RecruitingPhase 1/226 miles

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation

NCT03475212

The purpose of this study is to evaluate whether virus-specific T cell lines (VSTs) are safe and can effectively control three viruses (EBV, CMV, and adenovirus) in patients who have had a stem cell transplant and also in patients that have a primary immunodeficiency disorder with no prior stem cell transplant.

Cytomegalovirus InfectionsAdenovirus InfectionEBV Infection

Pediatric Transplantation & Cellular Therapy Consortium52 participantsStarted Jun 2018

Phoenix, Arizona, United States • Duarte, California, United States • Los Angeles, California, United States +27 more locations

Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation

Find Trials by Condition in Massachusetts

Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

Improving Clinical Efficiency by Reducing Scheduled Follow-ups Using Cochlear America's Population Mean Mapping Strategy

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

Collagen-targeted PET Imaging for Early Interstitial Lung Disease

Effect of a Probiotic Mixture on the Gut Microbiome and Fatigue in Patients With Quiescent Inflammatory Bowel Disease

Trauma Informed Guilt Reduction Therapy

The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

Optimizing Feedback-based Learning in Children With Developmental Language Disorder

Enhancing the Effects of Adolescent Alcohol Treatment With Atomoxetine

Clinical Trial Testing TH-302 in Combination With Gemcitabine in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma

A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease

A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma.

Efficacy in iNPH Shunting (PENS) Trial

A Study of SEA-CD40 Given With Other Drugs in Cancers

Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema

SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma