Clinical Trials in Cleveland

Showing 10461-10480 of 16,969 trials

Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial

NCT02950233

The objective of the PAIN-STOP trial is to assess the feasibility of a larger randomized controlled trial (RCT) evaluating NMDA antagonists and IV steroids, as compared to placebo, in decreasing the chances of clinically significant persistent post-surgical pain (PPSP) after video assisted thoracoscopic surgeries (VATS). This is a multi-centre randomized, controlled clinical trial with a 2 x 2 factorial design. The pilot phase of the trial will recruit 48 patients and follow them for 3 months. Patients will be randomized to one of four groups: 1) NMDA active + Steroid placebo; 2) Steroid active + NMDA placebo; 3) NMDA active + Steroid active; 4) NMDA placebo + Steroid placebo.

Pain, Postoperative

Population Health Research Institute27 participantsStarted May 2017

Cleveland, Ohio, United States • Hamilton, Ontario, Canada

COMPLETEDPhase 3< 1 mile

Evaluation of the Bioequivalence of Sprinkle and Capsule Formulations of Lubiprostone, as Compared to Placebo

NCT03097861

The purpose of this study is to evaluate the bioequivalence of sprinkle and capsule formulations of lubiprostone, as compared to placebo, when administered orally in participants with Chronic Idiopathic Constipation (CIC).

Chronic Idiopathic Constipation

Sucampo Pharma Americas, LLC552 participantsStarted Mar 2017

Birmingham, Alabama, United States • Foley, Alabama, United States • Little Rock, Arkansas, United States +64 more locations

Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial

Evaluation of the Bioequivalence of Sprinkle and Capsule Formulations of Lubiprostone, as Compared to Placebo

Find Trials by Condition in Cleveland

Genomics Used to Improve DEpression Decisions

Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in T-cell Lymphoma

Randomized, Double-blind, Multiple-site, Placebo-controlled, Parallel-design Study in Patients With Moderate to Severe Facial Erythema Associated With Rosacea

Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade

Opioid-induced Bowel Dysfunction: Long-Term Assessment of Lubiprostone

A Study to Look at Tapentadol Oral Solution in Children and Adolescents in Pain

Zenith® TX2® Low Profile TAA Endovascular Graft

Validation of Colon Biomarkers for the Early Detection of Colorectal Adenocarcinoma

An Investigation of ReNu™ Knee Injection in Patients With Osteoarthritis

Answer ALS: Individualized Initiative for ALS Discovery

Safety of PDT-Photofrin® Prior to Lung Surgery

Evaluation of Glucose Control in Patients With Diabetes

An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis

Farber Disease Natural History Study

Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye

A Non-Interventional Interview Study of Phenylketonuria (PKU) Adults

Comparison of a Rivaroxaban-based Strategy With an Antiplatelet-based Strategy Following Successful TAVR for the Prevention of Leaflet Thickening and Reduced Leaflet Motion as Evaluated by Four-dimensional, Volume-rendered Computed Tomography (4DCT)

A Phase 1/1b Study of MEDI3726 in Adults Subjects With Metastatic Castration Resistant Prostate Cancer