Clinical Trials in Cleveland

Showing 2501-2520 of 19,775 trials

Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)

NCT04869813

The goal of the proposed research is to investigate Magnetic Resonance (MR) Fingerprinting and P-MRS (Phosphorus-31 MR Spectroscopy) imaging for characterization of skeletal muscle in heart failure patients with sarcopenia. Heart failure patients with and without sarcopenia will be scanned using MR Fingerprinting and an existing Post-exercise phosphocreatine (PCr) recovery MR imaging protocol to obtain characteristic profiles of quantitative T1, T2, and PCr recovery rate.

Sarcopenia

The Cleveland Clinic70 participantsStarted Apr 2021

Cleveland, Ohio, United States

RECRUITINGPhase 3< 1 mile

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

NCT06318169

The study will assess the efficacy and safety of 2 dose regimens of pegozafermin compared to placebo for the treatment of liver fibrosis stage F2 or F3 in adult participants with MASH.

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

89bio, Inc.1,350 participantsStarted Mar 2024

Birmingham, Alabama, United States • Chandler, Arizona, United States • Flagstaff, Arizona, United States +328 more locations

Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Find Trials by Condition in Cleveland

Evaluation of Cochlear (Promontory) Stimulation During Awake Ear Surgery (TONES Study)

Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19

A Trial to Evaluate the Efficacy and Safety of Different Doses of LEO 138559 in Adults With Moderate-to-severe Atopic Dermatitis

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment

Study to Assess MEDI4736 With Either AZD9150 or AZD5069 in Advanced Solid Tumors & Relapsed Metastatic Squamous Cell Carcinoma of Head & Neck

Study of Single Agent Belantamab Mafodotin Versus Pomalidomide Plus Low-dose Dexamethasone (Pom/Dex) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

A Study of Navenibart in Participants With Hereditary Angioedema

Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI)

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease

Study of Anitocabtagene-autoleucel in Participants With Relapsed Refractory Multiple Myeloma

Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

Siplizumab in T1DM

A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial