Clinical Trials in Boston

Showing 1281-1300 of 17,836 trials

Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

NCT07087431

The goal of this clinical trial is to evaluate whether disclosure of a polygenic risk score for coronary artery disease (CAD PRS) influences cardiovascular health and risk factor modification over one year among adults aged 30-75 years in the Mass General Brigham primary care network who are not currently taking LDL cholesterol-lowering medications.

Coronary Artery Disease

Massachusetts General Hospital500 participantsStarted Oct 2025

Boston, Massachusetts, United States

RECRUITING< 1 mile

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

NCT04629014

This study proposes to quantify and describe the quality of life of children with intestinal failure, and to identify the medical and socio-economic factors that impact this quality of life, using data from multiple multidisciplinary intestinal failure centers across the United States and Canada specializing in the care of these participants.

Pediatric Intestinal Failure

Boston Children's Hospital750 participantsStarted Feb 2020

Birmingham, Alabama, United States • Aurora, Colorado, United States • Hartford, Connecticut, United States +11 more locations

Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

Find Trials by Condition in Boston

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer

Early Parkinson's Disease Monotherapy With CVN424

Neuroblastoma Biology Study

Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health

Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

Patient Reported Outcomes With WaveLight LASIK

A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform

Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas

Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia

Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

A Study to Assess the Safety, Pharmacokinetics, and Tolerability of ABI-1179 in Healthy Subjects and in Subjects Seropositive for HSV-2 With Recurrent Genital Herpes