Clinical Trials in Boston

Showing 10721-10740 of 15,299 trials

A Phase 2 Trial of Ponatinib in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor

NCT01874665

The purpose of this study is to evaluate the efficacy and safety of ponatinib in participants with metastatic and/or unresectable gastrointestinal stromal tumor (GIST) following failure of prior tyrosine kinase inhibitor (TKI) therapy.

GIST

Ariad Pharmaceuticals45 participantsStarted Jun 2013

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Portland, Oregon, United States +1 more locations

COMPLETEDNA< 1 mile

Effect of Gain on Closed-Loop Insulin

NCT02065895

The purpose of this study is to test the ability of an advanced external Physiologic Insulin Delivery (ePID) algorithm (a step by step process used to develop a solution to a problem) to get acceptable meal responses over a range of gain. Gain is defined as how much insulin is given in response to a change in a patient's glucose level. This study also examines the effectiveness of the external Physiologic Insulin Delivery (ePID) closed-loop insulin delivery computer software. The investigators would like to assess whether fasting target levels can be achieved as the closed-loop gain increases or decreases, and to evaluate the system's ability to produce an acceptable breakfast meal response.

Type 1 Diabetes

Joslin Diabetes Center8 participantsStarted Dec 2013

Boston, Massachusetts, United States

A Phase 2 Trial of Ponatinib in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor

Effect of Gain on Closed-Loop Insulin

Find Trials by Condition in Boston

Phase 1 and 2 Study of PX-866 and Cetuximab

Efficacy and Safety of Intravenous Neridronic Acid in CRPS-I

Double-Blind, Multi-Center, Randomized Study to Assess the Efficacy and Safety of Velneperit (S-2367) and Orlistat Administered Individually or Combined With a Reduced Calorie Diet (RCD) in Obese Subjects

A Study in Participants With Rheumatoid Arthritis

Substance Abuse Treatment to HIV Care (SAT2HIV): The Motivational Interviewing-based Brief Intervention Experiment

PF-00489791 For The Treatment Of Raynaud's

Salsalate as an Adjunctive Treatment for Patients With Schizophrenia

A Rheumatoid Arthritis Study in Participants on a Background Treatment of Methotrexate

Video Feedback Intervention for Cognitively Impaired Older Drivers

Transcranial Direct Current Stimulation Augmented Exposure and Response Prevention for Obsessive-Compulsive Disorder

A Study of Daclatasvir and Sofosbuvir With Ribavirin in Subjects With Cirrhosis and Genotype 3 Hepatitis C Infection

DFD06 Cream vs Clobetasol Propionate Cream, 0.05% Hypothalamic- Pituitary-Adrenal (HPA) Axis Suppression Study in Patients With Moderate to Severe Plaque Psoriasis

Radiosurgery or Open Surgery for Epilepsy Trial

Safety and Efficacy of NNC-0156-0000-0009 After Long-Term Exposure in Patients With Haemophilia B: An Extension to Trials NN7999-3747 and NN7999-3773

Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017

Study of Efficacy and Safety of Canakinumab in Patients With Hereditary Periodic Fevers

Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)

The Impact of Vitamin D on Disease Activity in Crohn's Disease