Salsalate as an Adjunctive Treatment for Patients With Schizophrenia

Exclusion Criteria

• •Inability to provide informed consent;
• •Current substance abuse;
• •Psychiatrically unstable per treating clinician's judgment;
• •Significant medical illnesses including uncontrolled hypertension, diabetes, seizure disorder, severe cardiovascular, cerebrovascular, pulmonary, or thyroid diseases;
• •Currently on immunosuppressant medication including oral steroids;
• •Use of anti-coagulants (heparin, LMWH, warfarin, cilostazol, clopidogrel, dabigatran);
• •History of chronic infection (including, HIV and hepatitis), malignancy, organ transplantation, blood dyscrasia, central nervous system demyelinating disorder, and any other known autoimmune or inflammatory condition;
• •Experienced asthma, urticaria or allergic type reaction after taking aspirin, salsalate, or other NSAIDS;
• •Pregnancy or breastfeeding;
• •Pre-existing chronic tinnitus.
• •Known hypersensitivity to salsalate.