Clinical Trials in Boston

Showing 10121-10140 of 15,299 trials

COMPLETEDPhase 4< 1 mile

Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)

NCT00464698

The purpose of this study is to assess the efficacy of Duloxetine in the treatment of obsessive compulsive disorder.

Obsessive Compulsive Disorder

Massachusetts General Hospital20 participantsStarted Dec 2005

Boston, Massachusetts, United States

COMPLETEDPhase 3< 1 mile

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

NCT01663402

Primary Objective: To compare the effect of alirocumab with placebo on the occurrence of cardiovascular (CV) events (composite endpoint of coronary heart disease (CHD) death, non-fatal myocardial infarction (MI), fatal and non-fatal ischemic stroke, unstable angina (UA) requiring hospitalization) in participants who experienced an acute coronary syndrome (ACS) event 4 to 52 weeks prior to randomization and were treated with evidence-based medical and dietary management of dyslipidemia. Secondary Objectives: * To evaluate the effect of alirocumab on secondary endpoints (any CHD event , major CHD event, any CV event, composite of all cause mortality/non-fatal MI/non-fatal ischemic stroke, CHD deaths, CV deaths, all cause mortality). * To evaluate the safety and tolerability of alirocumab. * To evaluate the effect of alirocumab on lipid parameters.

Atherosclerotic Cardiovascular Disease

Sanofi18,924 participantsStarted Oct 2012

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Huntsville, Alabama, United States +1385 more locations

Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Find Trials by Condition in Boston

Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation

Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiopulmonary Bypass

Emergency Department Safety Assessment and Follow-up Evaluation (ED-SAFE)

CRT Implant Strategy Using the Longest Electrical Delay for Non-left Bundle Branch Block Patients

Study to Evaluate Efficacy of CO-1.01 as Second Line Therapy for Gemcitabine-Refractory Stage IV Pancreatic Adenocarcinoma

Study of Itacitinib in Combination With Corticosteroids for the Treatment of Acute GVHD

Cessation of Long-term Opioid Therapy in Chronic Pain Patients

Implementation of CPT for PTSD in Diverse Communities

Efficacy, Safety, and Tolerability of Oral Ubrogepant in the Acute Treatment of Migraine

UltraShape Power for Abdominal Fat and Circumference Reduction

Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer

Edoxaban vs. Warfarin in Subjects Undergoing Cardioversion of Nonvalvular Atrial Fibrillation (NVAF)

Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation

A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt Nephropathy

A Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial Seizures

Moderate Alcohol and Cardiovascular Health Trial

Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)

An Efficacy and Safety Study of Ustekinumab in Participants With Active Nonradiographic Axial Spondyloarthritis