Clinical Trials in Boston

Showing 901-920 of 17,836 trials

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma

NCT00295919

RATIONALE: Drugs used in chemotherapy, such as fenretinide LXS, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase I trial is studying the side effects and best dose of fenretinide LXS in treating patients with recurrent, refractory, or persistent neuroblastoma.

Neuroblastoma

New Approaches to Neuroblastoma Therapy Consortium80 participantsStarted Dec 2005

Los Angeles, California, United States • Palo Alto, California, United States • San Francisco, California, United States +8 more locations

RECRUITINGPhase 1/2< 1 mile

A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas

NCT06090539

The purpose of this study is to evaluate the safety, tolerability, drug levels, and preliminary biological and clinical activity of BMS-986458, a bifunctional cereblon-dependent ligand-directed degrader of B-cell lymphoma 6 (BCL6), as a single agent and in combination with anti-lymphoma agents in participants with relapsed/refractory non-Hodgkin Lymphoma.

Relapsed/Refractory Non-Hodgkin Lymphoma

Bristol-Myers Squibb308 participantsStarted Dec 2023

Phoenix, Arizona, United States • Duarte, California, United States • Jacksonville, Florida, United States +62 more locations

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma

A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas

Find Trials by Condition in Boston

Delta GREENS Food is Medicine Intervention

An Expanded Access Program of Cretostimogene Grenadenorepvec for Treatment of NMIBC for Patients Unresponsive to BCG

The Effect of Sleep Loss on Emotion Regulation

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

A Study of XMT-1660 in Participants With Solid Tumors

Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension

Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer

Savolitinib vs. Sunitinib in MET-driven PRCC.

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis

SIMPLAAFY Clinical Trial

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

A Study of ZW251 in Participants With Advanced Solid Tumors

A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat ( SUPREME-02 )

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary Immunodeficiencies