Clinical Trials in Boston

Showing 8981-9000 of 17,836 trials

A Study of GMA301 in Subjects With Pulmonary Arterial Hypertension

NCT04503733

A Randomized, Placebo-Controlled, Double-blind, Dose Escalation Study to Assess Safety, Efficacy and Pharmacokinetics of GMA301 Injection in Subjects with Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Gmax Biopharm LLC.48 participantsStarted Oct 2020

Boston, Massachusetts, United States • Beijing, China • Changsha, China +4 more locations

COMPLETEDPhase 1< 1 mile

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

NCT03626012

The primary objective of this study is to evaluate the safety and tolerability of BIIB078 in adults with C9ORF72-Amyotrophic Lateral Sclerosis (ALS). The secondary objectives of this study are to evaluate the pharmacokinetic profile of BIIB078 and to evaluate the effects of BIIB078 on clinical function. As the first-in-human study, the study enrolls a small number of participants in each cohort. Every participant in a cohort is treated with the same dose or placebo. The study is designed to evaluate and confirm the safety of each dose before enrolling and exposing new participants to a higher dose in the next cohort.

Amyotrophic Lateral Sclerosis

Biogen106 participantsStarted Sep 2018

La Jolla, California, United States • Los Angeles, California, United States • Palo Alto, California, United States +18 more locations

A Study of GMA301 in Subjects With Pulmonary Arterial Hypertension

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

Find Trials by Condition in Boston

Motivational Interview Intervention to Help Patients Formulate Their Goals for Medical Care in the Emergency Department

Response to Relapse in Office-Based Opioid Treatment Trial

Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early Adenocarcinoma

EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options

Treatments for Anxiety: Meditation and Escitalopram

A Study to Evaluate the Long-Term Safety of Topical Administration of FMX103 in the Treatment of Moderate to Severe Papulopustular Rosacea

Research Study Comparing a New Medicine "Fast-acting Insulin Aspart" to Another Already Available Medicine "NovoRapid"/"NovoLog" in People With Type 2 Diabetes

A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin

Decitabine, Cytarabine, GCSF for Refractory AML/MDS

Lidocaine Infusion for Pain Relief in Children Scheduled for Tonsillectomy and Adenoidectomy

Clinical Evaluation of a Daily Wear Reusable Multifocal Optical Design in a Presbyopic Population

Early Coronary Angiography Versus Delayed Coronary Angiography

A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne

Improving Learning in Hispanics With TBI or MS

Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 1

Efficacy and Safety Study of Eravacycline Compared With Levofloxacin in Complicated Urinary Tract Infections

ERAS® Guidelines Validation of CRS With or Without HIPEC

Trial to Compare the Safety, Efficacy and Immunogenicity of TX05 With Herceptin® in HER2+ Early Breast Cancer