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Regional metabolic changes associated with response to 6 weeks of citalopram treatment, using 18-Fluorodeoxyglucose Positron Emission Tomography imaging, will be characterized (FDG PET).
Regional metabolic changes associated with response to 6 weeks of citalopram treatment, using 18-Fluorodeoxyglucose Positron Emission Tomography imaging, will be characterized (FDG PET). The following hypothesis will be tested: Antidepressant response or remission in depressed BPD patients will be associated with changes in cortical (prefrontal, parietal, premotor) and paralimbic (hippocampus, anterior cingulate, subgenual cingulate, posterior cingulate, and anterior insula) regions, consistent with SRI antidepressant response in unipolar depressed patients.
Age
18 - 64 years
Sex
ALL
Healthy Volunteers
No
Massachusetts General Hospital - East
Charlestown, Massachusetts, United States
Start Date
April 1, 2010
Primary Completion Date
December 1, 2013
Completion Date
December 1, 2013
Last Updated
March 7, 2019
60
ACTUAL participants
Lead Sponsor
Massachusetts General Hospital
NCT04480918
NCT06524505
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07172516