Clinical Trials in Boston

Showing 8801-8820 of 13,548 trials

Promoting Organizational Capacity to Implement Cancer Control Programs Among Latino Churches

NCT01740219

This research study aims to develop an organizational-level intervention to enable communities to adopt, adapt, implement and sustain evidence-based interventions (EBIs) to address cancer disparities among Latinos. The investigators partner with faith-based organizations, since they play a highly prominent role in Latino community life. This three-phase study will: (1) improve understanding of the organizational infrastructure, skills and resources required by Latino churches to implement EBIs for cancer control, (2) develop a capacity-building intervention; and (3) test the intervention's effectiveness in a randomized trial.

Cancer

Dana-Farber Cancer Institute348 participantsStarted Sep 2011

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Medford, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)

NCT02559570

The purpose of this study was to evaluate dose response of the safety and efficacy of linaclotide for the treatment of functional constipation (FC), in children age 6-17 years. This study includes up to a 4-week Screening Period, and a 2 to 3-week Pretreatment Period. Participants age 6-11 years will receive oral liquid formulation and participants 12-17 years will receive solid oral capsule or liquid oral solution. Children ages 6-11 years meeting the entry criteria will be randomized to 1 of 3 doses of linaclotide or placebo for 4 weeks. Children ages 12-17 years meeting the entry criteria will be randomized to 1 of 4 doses of linaclotide or placebo for 4 weeks. This 4-week study will assess the effects of linaclotide on bowel movement frequency, as well as other bowel symptoms of FC.

Functional Constipation in Children Ages 6-17 Years

Forest Laboratories173 participantsStarted Nov 2015

Hot Springs, Arkansas, United States • Little Rock, Arkansas, United States • Anaheim, California, United States +59 more locations

Promoting Organizational Capacity to Implement Cancer Control Programs Among Latino Churches

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)

Find Trials by Condition in Boston

Pilot Study Using Avastin and Gleevec to Treat the Progression of Intraluminal Pulmonary Vein Stenosis

Safety Study to Assess AFM11 in Patients With Relapsed and/or Refractory CD19 Positive B-cell NHL

The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C)

A Study to Evaluate the Safety of THR-149 in Subjects With Diabetic Macular Edema (DME)

A Trial Investigating the Efficacy and Safety of Insulin Degludec in Children and Adolescents With Type 1 Diabetes Mellitus

A Community-based Study to Target Childhood Obesity

A Study to Evaluate the Safety, Tolerability and Microbiome Dynamics of SER-287 in Subjects With Mild-to-Moderate Ulcerative Colitis

Storytelling Video Intervention for Depressed Primary Care Patients - Open Trial

Benralizumab Efficacy in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History

A Non-Invasive Neuromodulation Device for Prevention of Episodic Migraine Headache

Safety Evaluation of the GSK-580299 Vaccine in Women From the Control Group in the Primary NCT00294047 Study

Efficacy and Safety of Semaglutide Once-weekly Versus Exenatide ER 2.0 mg Once-weekly as add-on to 1-2 Oral Antidiabetic Drugs (OADs) in Subjects With Type 2 Diabetes

Safety and Effectiveness of B-Laser™ in Subjects Affected With Infrainguinal PAD

Cabazitaxel Versus the Switch to Alternative AR Targeted Therapy Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Primary Resistant Patients to Abiraterone or Enzalutamide

Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2

Long-term Safety and Tolerability of Cariprazine for Bipolar I Disorder

REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)

Clinical Evaluation of Visco-Assisted CyPass® Micro-Stent Implantation in Patients With Open Angle Glaucoma