Clinical Trials in Boston

Showing 7821-7840 of 13,548 trials

Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST)

NCT00135005

This study is an open-label, multicenter, Phase I dose-escalation study of the combination of AMN107 and imatinib (STI571) in patients with imatinib-resistant GIST. This study is designed to determine the Phase II dose of AMN107 and imatinib when administered together in patients with imatinib-resistant GIST, and to characterize the safety, tolerability and pharmacokinetic (PK) profile of this combination.

Gastrointestinal Stromal Tumors

Novartis Pharmaceuticals59 participantsStarted Aug 2005

Boston, Massachusetts, United States • Philadelphia, Pennsylvania, United States • Lyon, France +2 more locations

UNKNOWN< 1 mile

Use of Intrapyloric Botulinum Injections in Children

NCT04250844

This study aims to evaluate the effect of intrapyloric botulinum toxin in children with feeding disorders.

VomitingFeeding DisordersGastroparesis

Boston Children's Hospital100 participantsStarted Mar 2020

Boston, Massachusetts, United States

COMPLETEDPhase 3< 1 mile

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

NCT01371656

This randomized phase III trial studies how well levofloxacin works in preventing infection in young patients with acute leukemia receiving chemotherapy or undergoing stem cell transplant. Giving antibiotics may be effective in preventing or controlling early infection in patients receiving chemotherapy or undergoing stem cell transplant for acute leukemia. It is not yet known whether levofloxacin is effective in preventing infection.

Acute Leukemias of Ambiguous LineageBacterial InfectionDiarrhea+7 more

Children's Oncology Group624 participantsStarted Sep 2011

Little Rock, Arkansas, United States • Downey, California, United States • Duarte, California, United States +81 more locations

Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST)

Use of Intrapyloric Botulinum Injections in Children

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

Find Trials by Condition in Boston

A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of PF-06252616 in Duchenne Muscular Dystrophy

Study of Epratuzumab Versus Placebo in Subjects With Moderate to Severe General Systemic Lupus Erythematosus (SLE)

Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery

Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)

Follow-up of the PEPITES Study to Evaluate Long-term Efficacy and Safety of Viaskin Peanut in Children

COVID-19 Risk Stratification

Mental Imagery Therapy for Autism (MITA) - an Early Intervention Computerized Language Training Program for Children With ASD

Fluid Responsiveness Evaluation in Sepsis-associated Hypotension

The Assessment of Copper Parameters in Wilson Disease Participants on Standard of Care Treatment

Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 Diabetes

Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)

Spinal Cord Injury in the Pediatric Population - an International Multicenter Study

Safety and Efficacy of Turoctocog Alfa in Prevention and Treatment of Bleeds in Previously Untreated Children With Haemophilia A

Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2)

Efficacy and Safety of BCT197 in Subjects With Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease

A Study of HSP990 Administered by Mouth in Adult Patients With Advanced Solid Tumors

Combination of AUY922 With Trastuzumab in HER2+ Advanced Breast Cancer Patients Previously Treated With Trastuzumab