Clinical Trials in Boston

Showing 6061-6080 of 17,836 trials

The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

NCT03640325

Multisite Randomized Controlled Trial (RCT) testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults receiving hematopoietic cell transplantation for hematology malignancy.

CancerBone Marrow NeoplasmsAnxiety+5 more

Seattle Children's Hospital143 participantsStarted Apr 2019

Birmingham, Alabama, United States • Los Angeles, California, United States • Boston, Massachusetts, United States +2 more locations

RECRUITINGNA< 1 mile

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

NCT05327062

The objective of this prospective, multicenter controlled study is to assess the feasibility of a patient-tailored implantation by creating a cloud-based pre-procedural multimodality CRT-roadmap by integration of 3D images from 3D activation sequence from ECG, and coronary venous anatomy from cardiac computed tomography. This CRT-roadmap will be used to guide LV lead placement to a coronary vein in an electrically late-activated region. Study Hypothesis: At least 75% of patients undergoing a CRT implantation guided by non-invasive electrical and venous anatomy assessment (XSPLINE technology) will show a reduction of left ventricular end-systolic volume of 15% or more at 6-month evaluation.

Cardiac Resynchronization TherapyChronic Heart FailureLeft Bundle-Branch Block

XSpline S.p.A.150 participantsStarted Mar 2023

Chicago, Illinois, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +10 more locations

The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

Find Trials by Condition in Boston

A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT)

Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer

A Study to Evaluate the Safety of Long-term Ivacaftor Treatment in Participants With Cystic Fibrosis Who Are Less Than 24 Months of Age at Treatment Initiation and Have an Approved Ivacaftor-Responsive Mutation

Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases

Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial

A Study to Evaluate Safety, Tolerability and Immune Response in Adults Allergic to Peanut After Receiving Intradermal or Intramuscular Administration of ASP0892 (ARA-LAMP-vax), a Single Multivalent Peanut (Ara h1, h2, h3) Lysosomal Associated Membrane Protein DNA Plasmid Vaccine

A Study of Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue Sarcoma

Perfluorohexylcotane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Gobi Study)

tDCS to Decrease Opioid Relapse (UG3)

Rhode Island Asthma Integrated Response Program

Study of Novel Regimens in Relapsed or Refractory Multiple Myeloma

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 in Pneumococcal Vaccine-experienced Adults (V116-006, STRIDE-6)

A Study of Atezolizumab Compared With a Single-Agent Chemotherapy in Treatment Naïve Participants With Locally Advanced or Recurrent or Metastatic Non-Small Cell Lung Cancer Who Are Deemed Unsuitable For Platinum-Doublet Chemotherapy

First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas

Long Term Follow Up Protocol for NiCord®/CordIn™ (Omidubicel) Patients

Study of BGB-290 or Placebo in Participants With Advanced or Inoperable Gastric Cancer

A Study to Learn About the Effects of Sisunatovir in Infants With Respiratory Syncytial Virus Lower Respiratory Tract Infection.