Clinical Trials in Boston

Showing 5681-5700 of 17,836 trials

Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System

NCT04982406

This is a prospective observational study, the purpose of which is to: 1. Characterize response of the AV conduction system to TAVR with various prostheses by recording continuous His bundle electrograms during valve placement. 2. Correlate preprocedure ECG features with changes in AV nodal and infranodal conduction during placement of the valve prosthesis. 3. Correlate changes in AV nodal and infranodal conduction during the procedure with risk of developing AV conduction block after TAVR. 4. Assess the contribution of stressing the conduction system by atrial pacing prior to and following TAVR to prediction of postprocedural heart block. Assess the correlation between new onset bundle branch block, site and degree of conduction block or delay and subsequent development of high-grade or complete AV block.

Aortic StenosisTranscatheter Aortic Valve ReplacementHeart Block

Beth Israel Deaconess Medical Center409 participantsStarted May 2021

Boston, Massachusetts, United States

COMPLETED< 1 mile

Self-Assembling Matrix Forming Gel to Prevent Stricture Formation

NCT05581173

The study is designed as a multicenter prospective registry study evaluating the efficacy of the self-assembling peptide in the prevention of stricture formation after endoscopic resection as part of standard medical care. No experimental interventions will be performed.

Esophageal StrictureStricture

AdventHealth41 participantsStarted Sep 2022

Orlando, Florida, United States • Fort Wayne, Indiana, United States • Baltimore, Maryland, United States +3 more locations

Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System

Self-Assembling Matrix Forming Gel to Prevent Stricture Formation

Find Trials by Condition in Boston

The OPBC-07/microNAC Study

A Randomized Controlled Trial of Leg Length Discrepancy Techniques

BOTOX Effects on Seizure Severity and Susceptibility

Pilot Study of Rosuvastatin and Enoxaparin Thromboprophylaxis Following Ovarian Cancer Surgery (O-STAT Study)

Novel Experimental COVID-19 Therapies Affecting Host Response

The Gilenya Pregnancy Registry

A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Prevention of Childhood Maltreatment in Families With Young Children

Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation

Study of Capivasertib + Docetaxel vs Placebo + Docetaxel as Treatment for Metastatic Castration Resistant Prostate Cancer (mCRPC)

A Study of Elecsys® Troponin T hs Gen 6 in Participants With Symptoms of Acute Coronary Syndrome

A Study of Tirzepatide (LY3298176) in Participants With Nonalcoholic Steatohepatitis (NASH)

Intermediate-Size Expanded Access Protocol (EAP) for LP352

Extension to the MAGNIFY MS Trial on Mavenclad® (Magnify MS Extension)

Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) Pneumonia and Hyper-inflammation

International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab

International obServational sTudy on AiRway manaGement in operAting Room and Non-operaTing Room anaEsthesia

A Study to Investigate the Biological Effects of AZD9833 in Women With ER-positive, HER2 Negative Primary Breast Cancer