Clinical Trials in Boston

Showing 4961-4980 of 13,548 trials

Aspirin for the Treatment of Nonalcoholic Fatty Liver Disease

NCT04031729

Nonalcoholic fatty liver disease (NAFLD), defined by fatty infiltration of the liver in the absence of excess alcohol consumption, affects an estimated 30% of adults in the United States. A proportion of people with NAFLD will develop progressive, inflammatory nonalcoholic steatohepatitis (NASH), which can progress to liver cirrhosis and liver failure. NAFLD is expected to be the most common indication for liver transplantation by the year 2020. We hypothesize that among adults with NAFLD, aspirin will reduce intrahepatic lipid content, as quantified by 1H magnetic resonance spectroscopy (1H-MRS).

Nonalcoholic Fatty LiverNonalcoholic Steatohepatitis

Massachusetts General Hospital80 participantsStarted Sep 2019

Boston, Massachusetts, United States

TERMINATEDPhase 1/2< 1 mile

Use of Oxandrolone to Promote Growth in Infants With HLHS

NCT04090697

The primary aim of this study is to determine if clinically relevant doses of buccally administered oxandrolone are safe and tolerable in neonates with hypoplastic left heart syndrome (HLHS) or other single right ventricular anomalies who have undergone a Norwood procedure. The secondary aim is to evaluate the efficacy of buccally administered oxandrolone in improving objective indices of growth and nutrition in neonates who have undergone a Norwood procedure.

Hypoplastic Left HeartCongenital Heart Disease

Carelon Research34 participantsStarted Dec 2019

Atlanta, Georgia, United States • Boston, Massachusetts, United States • Ann Arbor, Michigan, United States +7 more locations

Aspirin for the Treatment of Nonalcoholic Fatty Liver Disease

Use of Oxandrolone to Promote Growth in Infants With HLHS

Find Trials by Condition in Boston

Diuretic Comparison Project

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Parkinson's Disease in Asian Americans

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients

Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant

Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia

Mathematical Modeling to Predict the Duration of Thrombocytopenia in Neonates

Modulating Brain Activity to Improve Goal-directed Physical Activity in Older Adults

A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss

Feasibility of Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic, Severe Aortic Stenosis

A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program

Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patients

An Exploratory Study of the Effects of Nivolumab Combined With Ipilimumab in Patients With Treatment-Naive Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC)

89Zr-TLX250 for PET/CT Imaging of ccRCC- ZIRCON Study

A Pilot Trial of Lithium in Subjects With Progressive Supranuclear Palsy or Corticobasal Degeneration

Comparative Performance of a Vaginal Yeast Test

Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 2

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062)