Stopping Aminosalicylate Therapy in Inactive Crohn's Disease

Exclusion Criteria

• •A current diagnosis of UC, indeterminate colitis, microscopic colitis, or diverticular disease-associated colitis
• •A diagnosis of short-bowel syndrome
• •Active perianal disease
• •Active fistulizing disease
• •A flare of CD within 3 months prior to enrollment requiring initiation/escalation of medical therapy or surgery
• •Use of systemic corticosteroids for CD (2 continuous weeks or more) within 3 months prior to enrollment
• •Any major resective bowel surgery for CD (ileal resection, ileocecal resection, proctocolectomy, colectomy, enterectomy, ostomy formation and repair, anastomosis/reanastomosis) within 6 months prior to enrollment
• •Unwillingness to stop taking aminosalicylates for the duration of the trial
• •Untreated bile salt malabsorption that, in the opinion of the investigator, may interfere with accurate study HBI assessment
• •Serious underlying disease other than CD that, in the opinion of the investigator, may interfere with the subject's ability to participate fully in the study
• •History of active alcohol or drug abuse that, in the opinion of the investigator, may interfere with the subject's ability to comply with the study procedures
• •Currently participating in another interventional trial, or previous participation within the last 3 months