Clinical Trials in Boston

Showing 3521-3540 of 11,579 trials

Effects of a Single Bout of Exercise on Transcriptomics and Metabolomics in Adipose Tissue

NCT04865965

The purpose of this study is to determine the effects of a single bout of exercise on changes in the genes and small molecules in blood and fat tissue, before and after a bout of exercise. This research may contribute to a better understanding of the beneficial effects of exercise on the body.

ObesityMetabolic Complication

Joslin Diabetes Center16 participantsStarted May 2021

Boston, Massachusetts, United States

COMPLETEDPhase 1< 1 mile

Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas

NCT06120036

This study will evaluate the tolerability and effectiveness of two treatments in Neurofibromatosis Type 1 Cutaneous Neurofibromas. These treatments are: Kybella and Asclera injection. Each patient will have a treatment and a control site.

Neurofibromatosis 1

Massachusetts General Hospital20 participantsStarted Dec 2022

Boston, Massachusetts, United States

COMPLETEDPhase 1< 1 mile

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

NCT04730583

This study will evaluate the tolerability and effectiveness of three FDA-approved treatments in Neurofibromatosis Type 1 Cutaneous Neurofibromas. These treatments are: a 1064nm laser, a 755nm laser, and a Kybella injection. Each patient will have a treatment and a control site.

Cutaneous Neurofibroma

Massachusetts General Hospital34 participantsStarted Jun 2021

Boston, Massachusetts, United States

COMPLETED< 1 mile

FUnctional diagnoSIs of corONary Stenosis (FUSION)

NCT04356027

The purpose of the FUSION study is to validate the diagnostic performance of Virtual Flow Reserve (VFR) by comparing it against a reference standard, fractional flow reserve (FFR).

Coronary Artery DiseaseCoronary Stenosis

Abbott Medical Devices312 participantsStarted Jun 2020

Huntsville, Alabama, United States • Scottsdale, Arizona, United States • Little Rock, Arkansas, United States +25 more locations

Effects of a Single Bout of Exercise on Transcriptomics and Metabolomics in Adipose Tissue

Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

FUnctional diagnoSIs of corONary Stenosis (FUSION)

Find Trials by Condition in Boston

Study to Determine the Efficacy and Safety of Romosozumab in the Treatment of Postmenopausal Women With Osteoporosis

Long-term Follow-up of Participants With Cerebral Adrenoleukodystrophy Who Were Treated With Lenti-D Drug Product

Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening

Continuation Study With Budesonide Oral Suspension (BOS) for Adolescent and Adult Participants With Eosinophilic Esophagitis (EoE)

Persona Partial Knee Clinical Outcomes Study

A Clinical Trial to Assess Subjects With Dry Eye Disease.

A Phase 3 Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer

Trial to Assess Safety and Efficacy of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN)

BioProtect Balloon Implant™ Balloon System Pivotal Study BP-007

A Clinical Trial to Determine the Long-term Safety and Tolerability of an Investigational Drug in People With Major Depressive Episode Associated With Bipolar I Disorder (Bipolar I Depression).

Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction

A Clinical Trial to Compare Topical Agents in Adults With Mild to Moderate Atopic Dermatitis (AD)

Efficacy and Safety of Calcipotriol Plus Betamethasone Gel in the Treatment of Scalp Psoriasis

Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors

Study of REGN6569 and Cemiplimab in Adult Patients With Advanced Solid Tumor Malignancies

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis