Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Massachusetts General Hospital
With
Dana-Farber Cancer Institute
If you are eligible to participate in this study you will have a pre-treatment FLT-PET scan within 7 days before starting treatment with radiation and temozolomide.
Two intravenous catheters (IVs) will be placed for each scan. One IV will be used to inject the FLT for the PET scan and the contrast agent for the MRI scan. The second IV will be used to draw blood for research tests. The PET scan will take about 2 hours. The MRI scan will take about 60-75 minutes. They will be done simultaneously.
About 4 weeks after you finish radiation therapy you will have a second FLT-PET scan and MRI scan.
Planned treatment for glioblastoma is standard radiation and temozolomide
Measurable disease
Life expectancy \>/= 12 weeks
Lab values must be within limits specified in protocol
Able to undergo MRI and PET scans
On stable dose of steroids for 5 days prior to each MRI scan
You may not be if
Chemotherapy or radiotherapy within 4 weeks (6 weeks for nitrosoureas or mitomycin C) prior to entering study or not recovered from adverse events from prior therapy
Receiving any other study agents to treat tumor
History of allergic reactions to compounds of similar chemical or biologic composition to FLT
