Clinical Trials in Boston

Showing 3461-3480 of 17,836 trials

Preventing Disordered Eating and Body Dissatisfaction Among High-risk Pregnant Individuals

NCT06659354

The investigators aim to conduct a feasibility randomized controlled trial (RCT) of an eating disorder prevention program (The Body Project, adapted for pregnancy) versus a health education control among pregnant individuals with histories of an ED. The investigators will test the feasibility, implementation outcomes, and its preliminary effectiveness in reducing the risk of elevated disordered eating and body dissatisfaction during pregnancy and postpartum.

Eating DisordersBody Dissatisfaction

Massachusetts General Hospital60 participantsStarted Jun 2024

Boston, Massachusetts, United States

Active Not RecruitingPhase 1/2< 1 mile

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

NCT05275478

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an open-label, dose escalation and the second part is an open label dose expansion in specific MTAP-deleted tumor types. The study drug, TNG908, is a selective PRMT5 inhibitor administered orally. The study is planned to treat up to 192 participants.

Locally Advanced Solid Tumor

Tango Therapeutics, Inc.192 participantsStarted Mar 2022

Los Angeles, California, United States • San Francisco, California, United States • Denver, Colorado, United States +17 more locations

Preventing Disordered Eating and Body Dissatisfaction Among High-risk Pregnant Individuals

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Find Trials by Condition in Boston

M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

Ipilimumab and Nivolumab in Leptomeningeal Metastases

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

Delirium in Children Undergoing Stem Cell Transplantation

Molecular Imaging of Primary Amyloid Cardiomyopathy

A Study of PF-06873600 in People With Cancer

Emapalumab Prevention of CAR-T Cell Associated Toxicities

REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study

Stereotactic Magnetic Resonance Guided Radiation Therapy

Association of Digital Aid Use With Infant Sleep and Maternal Mental Health

A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)

Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2

SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM

Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease

A Study Investigating Long-term Treatment With Spesolimab in People With a Skin Disease Called Hidradenitis Suppurativa Who Completed a Previous Clinical Trial

A Trial Evaluating TG4050 in Ovarian Carcinoma.

B-PaLMZ for TB Meningitis