Clinical Trials in Boston

Showing 3261-3280 of 8,503 trials

COMbination of Bipolar Androgen Therapy and Nivolumab

NCT03554317

Single arm, multicenter, open-label Phase II study of the effects of parenteral testosterone in combination with nivolumab in men with metastatic castration-resistant prostate cancer who previously progressed on at least one novel androgen-receptor targeted therapy (i.e. Abiraterone acetate, Enzalutamide). Up to one taxane agent is permitted.

Castration-resistant Prostate CancerMetastatic Prostate CancerProstate Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins45 participantsStarted Sep 2018

San Francisco, California, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States

TERMINATEDPhase 1< 1 mile

DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST)

NCT04276415

This study will assess the safety, efficacy, and pharmacokinetics of DS-6157a in participants with advanced gastrointestinal stromal tumors (GIST).

Gastrointestinal Stromal Tumors

Daiichi Sankyo34 participantsStarted May 2020

Boston, Massachusetts, United States • St Louis, Missouri, United States • Portland, Oregon, United States +2 more locations

COMbination of Bipolar Androgen Therapy and Nivolumab

DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST)

Find Trials by Condition in Boston

Prospective Comparison of Revolve™ and AuraGen 123 With AuraClens™ in Autologous Fat Grafting to the Breast

Safety & Effectiveness of Duodenal Mucosal Resurfacing (DMR) Using the Revita™ System in Treatment of Type 2 Diabetes

A Study of H3B-8800 (RVT-2001) in Participants With Lower Risk Myelodysplastic Syndromes

PF-07304814 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study

Merotocin in Mothers With Inadequate Milk Production and Infants Delivered Prematurely

Study in Pediatric Subjects With Peanut Allergy to Evaluate Efficacy and Safety of Dupilumab as Adjunct to AR101 (Peanut Oral Immunotherapy)

The Feasibility of VR for OUD

Practice of Acceptance, Awareness, and Compassion in Caregiving (PAACC)

A Long-Term Safety Trial of LUM-201 in Children With Idiopathic Growth Hormone Deficiency Who Have Previously Completed a LUM-201 Clinical Trial (OraGrowtH211)

Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy

Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA)

A Study of AL101 Monotherapy in Patients With Notch Activated Triple Negative Breast Cancer

REDUCE LAP-HFREF TRIAL

A Study Of Safety, Tolerability And Effectiveness Of Recifercept In Children With Achondroplasia

Lung EpiCheck Biomarkers Development Study

Double-Blinded, Placebo-Controlled Phase 1b Study for Safety, PK, Efficacy, PD of RO7049665 in Participants With Ulcerative Colitis (UC)

Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis