Clinical Trials in Boston

Showing 3241-3260 of 8,503 trials

Physical Activity Monitoring in Myasthenia Gravis

NCT06277830

The goal of this observational study is to evaluate the feasibility of using wearable sensor and digital technologies to measure motor and speech function in adults with autoimmune Myasthenia Gravis (MG). The main question\[s\] it aims to answer are: * To measure the correlation of sensor-based measures of motor function with existing outcome measures including the MG-ADL, MGQOL15r, QMG, MGComposite, and Neuro-QOL Fatigue scales. * To develop and validate tablet-based digital assessments of speech and facial expression and to compare with existing outcome measures. Participants will wear a pendant sensor for 7 days and then participate in tablet-based and in-person myasthenia-specific physical examinations. This will be performed in concert with routine care in the Massachusetts General Hospital MG clinic.

Myasthenia Gravis

Massachusetts General Hospital20 participantsStarted Feb 2024

Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19

NCT04372628

Blinded, multicenter, placebo-controlled, randomized clinical trial evaluating lopinavir/ritonavir vs placebo in early outpatient treatment of adults with COVID-19

COVID-19

Vanderbilt University Medical Center452 participantsStarted Jun 2020

Aurora, Colorado, United States • Boston, Massachusetts, United States • Jackson, Mississippi, United States +3 more locations

COMPLETEDPhase 2< 1 mile

An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Duodenitis

NCT03664960

This is a Phase 2, open-label, extension study to assess the safety and tolerability of AK002, given monthly for up to 26 doses.

Eosinophilic GastritisEosinophilic GastroenteritisEosinophilic Duodenitis

Allakos Inc.58 participantsStarted Nov 2018

Phoenix, Arizona, United States • Scottsdale, Arizona, United States • Ventura, California, United States +14 more locations

Physical Activity Monitoring in Myasthenia Gravis

Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19

An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Duodenitis

Find Trials by Condition in Boston

OCS Lung System EXPAND II Trial

A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (mFOLFOX6) in Gastric/Gastroesophageal Junction Cancer

HCV-TARGET- Hepatitis C Therapeutic Registry and Research Network

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool

COMbination of Bipolar Androgen Therapy and Nivolumab

A Prospective, Global, Multi-center, Treatment Registry Study of Intravenous Immunoglobulin Maintenance Therapy in Alloantibody Positive Renal Allograft Recipients

Inflammation and Cardiovascular Health in Women

Study of Predictors of Clinical Outcomes in Patients With HR+ and HER2-low/Negative Breast Cancer

A Study of LY3471851 in Participants With Psoriasis

Pilot Prospective Study: Long-term Health of Living Kidney Donors

A Study to Compare Bempegaldesleukin (BEMPEG: NKTR-214) Combined With Nivolumab and Tyrosine Kinase Inhibitor (TKI) to Nivolumab and TKI Alone in Participants With Previously Untreated Kidney Cancer That is Advanced or Has Spread

Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab

Safety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer

Clinical Trial of a New Device for Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome

Cardionomic STOP-ADHF Study

A Study to Assess the Efficacy and Safety of AK002 in Subjects With Antihistamine-Resistant Chronic Urticaria