Clinical Trials in Boston

Showing 3081-3100 of 17,836 trials

Studying Pathways of Resistance in KRAS-driven Cancers

NCT05272423

Up to 250 patients from anywhere in the United States can remotely consent and participate to have plasma drawn locally and submitted to Foundation Medicine, Inc. (FMI), for the FoundationOne® Liquid Biopsy Assay. Patients who have had resistance mechanisms determined through other assays can also consent to share these data. The Investigator(s) will compare mechanisms of acquired resistance across drugs (e.g. sotorasib vs adagrasib) and between tumor types (e.g. NSCLC vs CRC) to determine if different resistance mutations arise in these settings.

KRAS P.G12C

Addario Lung Cancer Medical Institute500 participantsStarted Sep 2022

Boston, Massachusetts, United States

Active Not RecruitingNA< 1 mile

Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)

NCT01653678

The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,875 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram) reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses. The VITAL Hypertension ancillary study is being conducted among participants in VITAL and will examine whether vitamin D or omega-3 fatty acids are related to changes in blood pressure and hypertension.

Hypertension

Brigham and Women's Hospital25,875 participantsStarted Nov 2011

Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease

NCT06001177

The study goal is to evaluate the efficacy, safety, and tolerability of KAN-101 in participants with Celiac Disease (CeD)

Celiac DiseaseCoeliac Disease

Kanyos Bio, Inc., a wholly-owned subsidiary of Anokion SA55 participantsStarted Dec 2023

Colorado Springs, Colorado, United States • Hialeah Gardens, Florida, United States • Miami, Florida, United States +25 more locations

Studying Pathways of Resistance in KRAS-driven Cancers

Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease

Find Trials by Condition in Boston

Omnipod® SmartAdjust 2.0 System Compared to the Omnipod® 5 System in Individuals With Type 1 or Type 2 Diabetes

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Multisite Virtual Reality Intervention for Speech Anxiety

A Study of GSK5764227 in Participants With. Advanced Solid Tumors (EMBOLD PanTumor-101)

HAELO: A Phase 3 Study to Evaluate NTLA-2002 in Participants With Hereditary Angioedema (HAE)

DCS Study in Extremely Premature Newborns

Electrostimulation Study for Ocular Graft vs. Host Disease

Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome

Telehealth to Improve Prevention of Suicide (TIPS)

SyncAV Post-Market Trial

A Phase II Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer

STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer

Long-Term Follow-Up (LTFU) for Gene Therapy of Leukocyte Adhesion Deficiency-I (LAD-I)

An Observational LTFU Study for Patients Previously Treated With Autologous ex Vivo Gene Therapy for ADA-SCID