Clinical Trials in Boston

Showing 3021-3040 of 17,836 trials

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

NCT06239116

The purpose of this study is to evaluate the safety, tolerability, and PK of RM-718 in healthy subjects with obesity and in patients with MC4R Pathway Impairment

Hypothalamic ObesityPrader-Willi SyndromePWS

Rhythm Pharmaceuticals, Inc.150 participantsStarted Mar 2024

Birmingham, Alabama, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +4 more locations

RECRUITINGPhase 2< 1 mile

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

NCT06735248

The primary objective of this trial is to evaluate the safety and reactogenicity of mRNA-1195 in participants with multiple sclerosis.

Multiple Sclerosis

ModernaTX, Inc.180 participantsStarted Apr 2025

Boston, Massachusetts, United States • Farmington Hills, Michigan, United States • Ozark, Missouri, United States +14 more locations

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

Find Trials by Condition in Boston

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

Circadian Influence on Prolonged Exposure Therapy for PTSD

Pembrolizumab With Carboplatin Compared to Carboplatin Alone in Breast Cancer Patients With Chest Wall Disease

Impact of Community Health Workers on Adherence to Therapy for Non-Communicable Chronic Disease in Chiapas, Mexico

Advanced XLIF Monitoring Multicenter Study

Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)

A Study of AMG 355 Alone and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV)

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Imaging Histone Deacetylase in the Heart

A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease

ARISe at UMass Chan

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.

A Trial to Assess the Long-term Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly

Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout

A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis