Clinical Trials in Boston

Showing 3001-3020 of 17,836 trials

Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

NCT04997902

This phase 1/2 combination trial of tipifarnib, a farnesyltransferase inhibitor, and alpelisib, a PI3K inhibitor in participants with recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) whose tumors overexpress the HRAS protein and/or are PIK3CA-mutated and/or PIK3CA-amplified.

HNSCC

Kura Oncology, Inc.45 participantsStarted Dec 2021

Duarte, California, United States • Orlando, Florida, United States • Baltimore, Maryland, United States +8 more locations

Active Not RecruitingPhase 2< 1 mile

Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)

NCT03331250

This research study is studying a drug as a possible treatment for Angiosarcoma or Epithelioid hemangioendothelioma (EHE). -The drug involved in this study is Eribulin

AngiosarcomaEpithelioid Hemangioendothelioma

Massachusetts General Hospital13 participantsStarted Jan 2018

Boston, Massachusetts, United States • Boston, Massachusetts, United States

Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)

Find Trials by Condition in Boston

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

Kidney Blood Flow During Exercise in Older African American Adults

A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)

Novel PET/CT and Treatment Strategies to Reduce PTS Following DVT

A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

SP Thoracic IDE Study

Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients

Advanced XLIF Monitoring Multicenter Study

Ribociclib and Letrozole Treatment in Ovarian Cancer

Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

Safety and Efficacy of Turoctocog Alfa Pegol (N8-GP) in Previously Untreated Patients With Haemophilia A

Safety and Efficacy of Nonacog Beta Pegol (N9-GP) in Previously Untreated Patients With Haemophilia B

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders

Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy

Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies