Clinical Trials in Boston

Showing 2441-2460 of 8,503 trials

Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue

NCT06740526

This is a phase 2b open-label trial to characterize histopathological biomarkers of disease in immunoglobulin A nephropathy (IgAN) and demonstrate potential changes in response to sibeprenlimab.

IgA Nephropathy

Otsuka Pharmaceutical Development & Commercialization, Inc.25 participantsStarted Nov 2024

Denver, Colorado, United States • Boston, Massachusetts, United States • Dakota Dunes, South Dakota, United States +2 more locations

Not Yet RecruitingPhase 1< 1 mile

Safety Study of XT-150 in Participants With ALS

NCT06704347

This is a Phase 1, open-label, multi-center safety study of XT-150 in adult participants with Amyotrophic Lateral Sclerosis (ALS). Participants providing informed consent and meeting all study eligibility criteria will be enrolled in the study and will receive a single injection of XT-150 at the Baseline visit. Follow-up visits will occur over 180 days (6 months) after the injection. 8 participants (4 participants per dose level) will be enrolled sequentially in up to 2 ascending, single dose cohorts: Cohort 1: 1.5 mg XT-150 Cohort 2: 4.5 mg XT-150

Amyotrophic Lateral Sclerosis (ALS)

Xalud Therapeutics, Inc.8 participantsStarted Nov 2025

Phoenix, Arizona, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +1 more locations

RECRUITINGNA< 1 mile

A Future Thinking Intervention for Comorbid Tobacco Use Disorder and Bipolar Disorder

NCT06609902

Future Self-BD is a 6-session virtual intervention that encourages participants to vividly generate personal and positive future events that they anticipate may be benefited by smoking cessation. Each session will be conducted on HIPAA-compliant Zoom and led by the PI (Dr. Gold).

Bipolar DisorderTobacco Use Disorder

Massachusetts General Hospital70 participantsStarted Dec 2024

Boston, Massachusetts, United States

Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue

Safety Study of XT-150 in Participants With ALS

A Future Thinking Intervention for Comorbid Tobacco Use Disorder and Bipolar Disorder

Find Trials by Condition in Boston

A Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) Metastatic or Locally Advanced Breast Cancer

HEART at Head Start Pilot (Healthy Eating, Activity, Relaxation Trial)

ADH1 and ADH2 Disease Monitoring Study (DMS)

Evaluation of Exotropia After Patching the Eye or After Prism Adaptation

Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

Tai Chi and Wellness Education for Older Veterans

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

Continuing the Conversation: Using Narrative Communication to Support Hypertension Self-management in African American Veterans

Adherence to Universal Aspirin Compared to Screening Indicated Aspirin for Prevention of Preeclampsia

Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation

Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)

A Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque Psoriasis

A Study of the Change in Early and Sustained Pain Control in Axial Spondylarthritis in Adult Participants Receiving Upadacitinib

Long Term Follow-up of HPV Vaccine in HIV (CTN 236)

Study of WAL0921 in Patients With Glomerular Kidney Diseases

Effect of Tusamitamab Ravtansine on QTc Interval in Participants With Metastatic Solid Tumors