Clinical Trials in Boston

Showing 2321-2340 of 8,503 trials

The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)

NCT06315023

The purpose of this post-market surveillance study will be to evaluate the real-world use of the DETOUR System in treated patients with symptomatic femoropopliteal lesions from 200 mm to 460 mm in length with chronic total occlusions (100 mm to 425 mm) or diffuse stenosis \> 70% who may be considered suboptimal candidates for surgical or alternative endovascular treatments.

Peripheral Arterial DiseaseSymptomatic Femoropopliteal Lesions

Endologix450 participantsStarted Oct 2023

Salinas, California, United States • Storrs, Connecticut, United States • Washington D.C., District of Columbia, United States +7 more locations

RECRUITINGNA< 1 mile

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

NCT05103566

This is a single-site, single-arm, open-label pilot study assessing the safety, feasibility, and efficacy of non-invasive vagus nerve stimulation (nVNS), gammaCore, for the acute treatment of aneurysmal subarachnoid hemorrhage (SAH) subjects in a neurocritical care setting. 25 patients will be enrolled, all treated with an active device. The primary efficacy outcomes are reduced aneurysm rupture rate, reduced seizure and seizure-spectrum activity, minimized hemorrhage grades, and increased survival.

Subarachnoid Hemorrhage, Aneurysmal

Massachusetts General Hospital25 participantsStarted Oct 2022

Boston, Massachusetts, United States

The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

Find Trials by Condition in Boston

Collagen-targeted PET Imaging for Early Interstitial Lung Disease

Trauma Informed Guilt Reduction Therapy

LY3214996 in Patients With AML Who Are Not Candidates for Standard Therapy

A Retrospective and Prospective Natural History of Genetic Vasculopathies

Optimizing Feedback-based Learning in Children With Developmental Language Disorder

Mucolipidosis Type IV Natural History Study

The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC

Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans

Interpretation Bias as a Mechanism of Treatment Response in OCD

Enhancing the Effects of Adolescent Alcohol Treatment With Atomoxetine

Efficacy in iNPH Shunting (PENS) Trial

Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM

PRV-3279-2a Trial in Systemic Lupus

SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma